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Chemical Structure| 68701-52-0 Chemical Structure| 68701-52-0

Structure of 68701-52-0

Chemical Structure| 68701-52-0

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Product Details of [ 68701-52-0 ]

CAS No. :68701-52-0
Formula : C11H14N2O2
M.W : 206.24
SMILES Code : O=C(NC1=CC=C(C(C)C)C=C1)/C=N/O

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 68701-52-0 ]

[ 68701-52-0 ] Synthesis Path-Upstream   1~1

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  • [ 68701-52-0 ]
  • [ 150560-58-0 ]
YieldReaction ConditionsOperation in experiment
98.7% at 20 - 30℃; for 2.16667 h; To 294 g of 95percent sulfuric acid was added 41.2 g of isonitrosoaceto-p-isopropylanilide at room temperature. Then, the temperature was raised to 30 ° C. over 10 minutes, and the mixture was stirred at the same temperature for 2 hours. After completion of the reaction, the reaction solution was added dropwise to a separate vessel charged with 419 g of water, and the precipitate was filtered. Washed with 1,300 g of water and dried in a dryer at 60 ° C. to obtain 37.3 g of 5-isopropyl isatin. The yield was 98.7percent, the purity was 98.1 wtpercent, and the melting point was 137 to 140 ° C. In this example, the molar ratio of isonitrosoaceto-p-isopropylanilide to sulfuric acid is 1: 14.3.
References: [1] Patent: JP2018/150285, 2018, A, . Location in patent: Paragraph 0024-0031; 0036.
[2] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004, vol. 43, # 7, p. 1585 - 1587.
 

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