Home Cart Sign in  
Chemical Structure| 694-32-6 Chemical Structure| 694-32-6
Chemical Structure| 694-32-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Synonyms: 2-imidazolidinone, 1-methyl-

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

DE Stock

US Stock

Asia Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of 1-Methylimidazolidin-2-one

CAS No. :694-32-6
Formula : C4H8N2O
M.W : 100.12
SMILES Code : O=C1NCCN1C
Synonyms :
2-imidazolidinone, 1-methyl-
MDL No. :MFCD00800601
InChI Key :JTPZTKBRUCILQD-UHFFFAOYSA-N
Pubchem ID :567600

Safety of 1-Methylimidazolidin-2-one

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 1-Methylimidazolidin-2-one

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 694-32-6 ]

[ 694-32-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 694-32-6 ]
  • [ 101990-45-8 ]
  • 5-((1H-imidazol-1-yl)methyl)-2-bromopyridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
26% With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20℃; Step 1: Synthesis of 5- ((1H-imidazol- 1 -yl)methyl)-2 -bromopyridine. The starting material 2-bromo-5-(bromomethyl)pyridine was synthesized according to a published protocol (Tetr. Lett. 2002, 43, 1697). To a 50 mL round bottom flask containing 1-methyl-2-imidazolidinone (250 mg, 2.5 mmol) and Nail 60%dispersion in mineral oil (110 mg, 2.75 mmol, 1.1 eq) at 0C was added 3 mL of DriSolv DMF. The reaction turned into a cloudy white solid, then warmed to room temperature, and stirred for an hour. 2-bromo-5-(bromomethyl)pyridine (750 mg, 1.2 mmol, 3 eq) was dissolved in 1 mL of DriSolv DMF and the reaction was stirred overnight at room temperature. The reaction wasconcentrated in vacuo, dissolved in EtOAc and a saturated solution of NH4C1, and extracted. The organic layer was concentrated in vacuo, and purified by automated chromatography to yield 173 mg (26%) of a light brown oil R 0.15 in 75% EtOAc in hexanes 1% MeOH). ‘H NMR (600 MHz, CD3OD) d 8.26 (d, Jz 2.4 Hz, 1H), 7.62 (dd, J 8.2, 2.5 Hz, 1H), 7.56 (d, J 8.2 Hz, lET), 4.33 (s,2H), 3.36 - 3.31 (m, 2H), 3.28 - 3.23 (m, 2H), 2.77 (s, 3ET). 13C NMR (151 MHz, CD3OD) d 150.70, 141.72, 140.28, 134.46, 129.45, 45.97, 45.95, 43.46, 31.40.
 

Historical Records

Technical Information

Categories