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Chemical Structure| 7008-63-1 Chemical Structure| 7008-63-1

Structure of 7008-63-1

Chemical Structure| 7008-63-1

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Product Details of [ 7008-63-1 ]

CAS No. :7008-63-1
Formula : C11H8N2S
M.W : 200.26
SMILES Code : C12=NC(C3=CC=CC=C3)=CN1C=CS2
MDL No. :MFCD00139581

Safety of [ 7008-63-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 7008-63-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7008-63-1 ]

[ 7008-63-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7008-63-1 ]
  • [ 14135-38-7 ]
  • 5-[(2-fluorophenyl)thio]-6-phenylimidazo[2,1-b]thiazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
93% With dihydrogen peroxide; iodine; In ethanol; at 25℃; for 18h;Green chemistry; General procedure: A 15-mL tube with a Teflon cap, equipped with a magnetic stirring bar, was charged with substrate 1a (0.20 mmol), diphenyl disulfide (0.10 mmol, 0.5 equiv), and I2 (20 mol percent); H2O2 (2 equiv) and EtOH (2mL) were then added sequentially. The tube was capped and stirred at 25 °C for 18 h, the crude mixture was diluted with EtOAc, and washed with sat. aq Na2S2O3 solution (3 × 10 mL). The organic phase was dried (MgSO4), filtered through a Celite pad, and washed with EtOAc. The filtrate was concentrated in vacuo, and the resulting residue was purified by column chromatography (hexane ? EtOAc) to afford product 3aa as a light yellow solid; yield: 56.8 mg (92percent).
 

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