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Chemical Structure| 7078-98-0 Chemical Structure| 7078-98-0

Structure of 7078-98-0

Chemical Structure| 7078-98-0

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Product Details of [ 7078-98-0 ]

CAS No. :7078-98-0
Formula : C21H26O
M.W : 294.43
SMILES Code : O=C1C(C(C)(C)C)=CC(C=C1C(C)(C)C)=CC2=CC=CC=C2
MDL No. :MFCD00514861
InChI Key :HCUWXYBKPSKTAB-UHFFFAOYSA-N
Pubchem ID :160881

Safety of [ 7078-98-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 7078-98-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7078-98-0 ]

[ 7078-98-0 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 4139-61-1 ]
  • [ 7078-98-0 ]
  • 3-((3,5-di-tert-butyl-4-hydroxyphenyl)(phenyl)methyl)-4-hydroxy-6-bromocoumarin [ No CAS ]
YieldReaction ConditionsOperation in experiment
87% With boron trifluoride diethyl etherate; In dichloromethane; at 20℃; for 24h; Take a reaction tube, add 2,6-di-tert-butyl-4-benzylidene cyclohexane-2,5-dienone (59 mg, 0.2 mmol,(0.7 mg, 0.24 mmol, 1.2 equiv), boron trifluoride diethyl ether (0.04 mmol, 0.2 equiv), 1 mL of dichloromethane at room temperature for 24 hours, The solvent was evaporated to dryness and separated by silica gel column to give 93 mg of product as a white solid, 87% yield.
  • 2
  • [ 7078-98-0 ]
  • [ 157869-15-3 ]
  • 2,6-di-tert-butyl-4-((2-(4-methoxyphenyl)-1H-indol-3-yl)(phenyl)methyl)phenol [ No CAS ]
  • 3
  • [ 7078-98-0 ]
  • [ 15754-51-5 ]
  • ((3,5-di-tert-butyl-4-hydroxyphenyl)(phenyl)methyl)bis(4-methoxyphenyl)phosphorus oxide [ No CAS ]
YieldReaction ConditionsOperation in experiment
96% With caesium carbonate; In acetonitrile; at 40℃; for 6h;Schlenk technique; Inert atmosphere; 131.0 mg (0.5 mmol) of <strong>[15754-51-5]bis(p-methoxyphenyl)phosphine oxide</strong>, 147.1 mg (0.5 mmol) 4-phenylmethylene-2,6-di-tert-butyl-2,5-cyclohexadien-1-one, 0.025 mmol of cesium carbonate was added to the Schlenk tube under nitrogen. 1.0 mL of acetonitrile was added under nitrogen, and the reaction was stirred at 40 C for 6 hours. After the reaction is completed, it is separated and purified by column chromatography, and the target product is obtained. The isolated yield of ((3,5-di-tert-butyl-4-hydroxyphenyl)(phenyl)methyl)bis(4-methoxyphenyl)phosphorus oxide was 96%.
  • 4
  • [ 7078-98-0 ]
  • [ 14752-66-0 ]
  • 2,6-di-tert-butyl-4-[(4-chlorophenyl)thio](phenyl)methyl}phenol [ No CAS ]
YieldReaction ConditionsOperation in experiment
91% With sulfuric acid; triphenylphosphine; In water; acetonitrile; at 80℃; for 3h;Schlenk technique; Inert atmosphere; Add 98.0 mg (0.5 mmol) of <strong>[14752-66-0]sodium 4-chlorobenzenesulfinate</strong>,176.4 mg (0.6 mmol) of 4-phenylmethylene-2,6-di-tert-butyl-2,5-cyclohexadien-1-one, 1.0 mmol of triphenylphosphine,1.0 mmol sulfuric acid is added to the Schlenk tube under nitrogen atmosphere,Add 1.0 mL acetonitrile and 1.0 mL water under nitrogen,Stir the reaction at 80 oC for 3 hours. After the reaction was completed, the product was separated and purified by column chromatography, and the yield of the target product was 91%.
 

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