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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Chemical Structure| 71322-99-1 Chemical Structure| 71322-99-1

Structure of 71322-99-1

Chemical Structure| 71322-99-1

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Product Details of [ 71322-99-1 ]

CAS No. :71322-99-1
Formula : C6H11NO
M.W : 113.16
SMILES Code : CC1CC(=O)CCN1
MDL No. :MFCD05861572

Safety of [ 71322-99-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H319-H225
Precautionary Statements:P210-P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362
Class:3
UN#:1993
Packing Group:

Application In Synthesis of [ 71322-99-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 71322-99-1 ]

[ 71322-99-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 71322-99-1 ]
  • [ 24424-99-5 ]
  • [ 790667-43-5 ]
  • [ 790667-49-1 ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; In diethyl ether; water; at 20℃; for 3h; Step 1 A solution of 0.52 g of 7-Methyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester), prepared according to the method of Beak at al. (J. Org. Chem. 1993,58,1109-1117), in 6 ml acetic acid and 2.5 ml concentrated HCl was stirred overnight at room temperature. The mixture was diluted with ethyl acetate and washed with 1N sodium hydroxide. The organic layer was dried over sodium sulfate and evalorated to give 0.29 g of a yellow oil. This was dissolved in 15 ml ether and treated with 5 ml 1N NaOH and 72 g (2.57 mmol) boc anhydride. The mixture was stirred for 3 hours at room temperature then diluted with ether and washed with 1N NaOH, water, and brine. The organic layer was dried over sodium sulfate and evaporated. The residue was purified by column chromatography over silica gel, eluding with 20% ethyl acetate in hexane to give 0.18 g of 1-tert-butoxycarbonyl-2-methyl-4-oxo-piperidine as a mixture of diastereomers.
 

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