Home Cart Sign in  
Chemical Structure| 72851-19-5 Chemical Structure| 72851-19-5

Structure of 72851-19-5

Chemical Structure| 72851-19-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 72851-19-5 ]

CAS No. :72851-19-5
Formula : C12H12F3NO
M.W : 243.23
SMILES Code : O=C(C1=CC=CC(C(F)(F)F)=C1)/C=C/N(C)C
MDL No. :MFCD01570011

Safety of [ 72851-19-5 ]

Application In Synthesis of [ 72851-19-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 72851-19-5 ]

[ 72851-19-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 72851-19-5 ]
  • [ 1450-93-7 ]
  • 5-(α,α,α-trifluoro-m-tolyl)imidazo[1,2-a]pyrimidine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium acetate; In hexane; dichloromethane; acetic acid; EXAMPLE 1 5-(alpha,alpha,alpha-Trifluoro-m-tolyl)imidazo[1,2-a]pyrimidine A mixture of 2.64 g of <strong>[1450-93-7]2-aminoimidazole hemisulfate</strong>, 1.64 g of anhydrous sodium acetate, 4.86 g of 3-dimethylamino-3'-(trifluoromethyl)-acrylophenone and 50 ml of glacial acetic acid was refluxed for six hours. The solvent was removed in vacuo to yield a crude solid. The solid was dissolved in dichloromethane and this solution was washed with saturated aqueous sodium bicarbonate solution. The organic layer was separated and dried over powdered anhydrous sodium sulfate. This solution was passed through a short column of a hydrous magnesium silicate and the effluent was refluxed on a steam bath with the gradual addition of hexane until turbidity was noted. After cooling the desired compound was collected by filtration and gave 1.20 g of pale yellow crystals, m.p. 160°-163° C.
 

Historical Records

Technical Information

Categories