[ CAS No. 7356-41-4 ] {[proInfo.proName]}

Name: 7356-41-4|2-(2,5-Dimethylphenoxy)acetic acid|95%
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SKU: A722885
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Quality Control of [ 7356-41-4 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 7356-41-4 ]

Product Details of [ 7356-41-4 ]

CAS No. :	7356-41-4	MDL No. :	MFCD00014356
Formula :	C₁₀H₁₂O₃	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	RSJMMLSDGNQOEO-UHFFFAOYSA-N
M.W :	180.20	Pubchem ID :	81817
Synonyms :

Calculated chemistry of [ 7356-41-4 ]

Physicochemical Properties

Num. heavy atoms :	13
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.3
Num. rotatable bonds :	3
Num. H-bond acceptors :	3.0
Num. H-bond donors :	1.0
Molar Refractivity :	49.44
TPSA :	46.53 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-5.74 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.66
Log Po/w (XLOGP3) :	2.34
Log Po/w (WLOGP) :	1.77
Log Po/w (MLOGP) :	1.67
Log Po/w (SILICOS-IT) :	2.04
Consensus Log Po/w :	1.9

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.85

Water Solubility

Log S (ESOL) :	-2.57
Solubility :	0.479 mg/ml ; 0.00266 mol/l
Class :	Soluble
Log S (Ali) :	-2.96
Solubility :	0.199 mg/ml ; 0.00111 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-2.69
Solubility :	0.368 mg/ml ; 0.00204 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.67

Safety of [ 7356-41-4 ]

Signal Word:	Danger	Class:	8
Precautionary Statements:	P264-P270-P273-P280-P301+P312+P330-P305+P351+P338+P310-P501	UN#:	3261
Hazard Statements:	H302-H318-H412	Packing Group:	Ⅲ
GHS Pictogram:

Application In Synthesis of [ 7356-41-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 7356-41-4 ]

[ 7356-41-4 ] Synthesis Path-Downstream 1~20

1
[ 95-87-4 ]
furan-2,3,5(4H)-trione pyridine (1:1) [ No CAS ]
[ 79-11-8 ]
[ 7356-41-4 ]

Reference： [1]Gluud; Breuer [Chemisches Zentralblatt, 1919, vol. 90, # I, p. 626]

2
[ 95-87-4 ]
[ 79-11-8 ]
[ 7356-41-4 ]

Yield	Reaction Conditions	Operation in experiment
82%	With sodium hydroxide In water at 60℃; for 7h;
	With sodium hydroxide
	With sodium hydroxide

	With sodium hydroxide Heating;
	With sodium hydroxide In water	General procedure for the synthesis of aryloxy acetic/propionicacids (2a-q and 3a-q) General procedure: Equimolar quantities of 2-chloro acetic acid/3-chloro propionicacid (0.05 mol) and appropriate phenol (1a-q) (0.05 mol) were taken in a conical flask, to which aqueous solution of NaOH(0.12 mol in 25 mL water) was slowly added with constant stirring.The solution was stirred for 2 h until the solution turned clear,brown or yellow and then the reaction mixture was evaporatedin a evaporating dish until the solid sodium salt was precipitated. The salt was isolated, dried, dissolved in water and acidified byadding con. HCl. The precipitated aryloxy acetic/propionic acidwas filtered and recrystallized from water or ethanol

Reference： [1]Del Carmen Cruz, María; Tamariz, Joaquín [Tetrahedron, 2005, vol. 61, # 42, p. 10061 - 10072]
[2]Gluud; Breuer [Chemisches Zentralblatt, 1919, vol. 90, # I, p. 626]
[3]Brueckner [Angewandte Chemie, 1928, vol. 41, p. 1046][Fresenius' Zeitschrift fuer Analytische Chemie, 1928, vol. 75, p. 290]
[4]Purohit; Shah [Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999, vol. 38, # 5, p. 618 - 622]
[5]Joshi, Shrinivas D.; More, Uttam A.; Koli, Deepshikha; Kulkarni, Manoj S.; Nadagouda, Mallikarjuna N.; Aminabhavi, Tejraj M. [Bioorganic Chemistry, 2015, vol. 59, p. 151 - 167]

3
[ 123-75-1 ]
[ 7356-41-4 ]
2-(2,5-Dimethyl-phenoxy)-1-pyrrolidin-1-yl-ethanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
67%	With dicyclohexyl-carbodiimide In diethyl ether for 14h; Ambient temperature;

Reference： [1]Chauhan, Jaya; Chauhan, J. S.; Gupta, P. P.; Srimal, R. C. [Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1993, vol. 32, # 2, p. 305 - 307]

4
[ 110-91-8 ]
[ 7356-41-4 ]
2-(2,5-Dimethyl-phenoxy)-1-morpholin-4-yl-ethanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
91%	With dicyclohexyl-carbodiimide In ethyl acetate for 14h; Ambient temperature;

Reference： [1]Chauhan, Jaya; Chauhan, J. S.; Gupta, P. P.; Srimal, R. C. [Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1993, vol. 32, # 2, p. 305 - 307]

5
[ 110-85-0 ]
[ 7356-41-4 ]
2-(2,5-Dimethyl-phenoxy)-1-{4-[2-(2,5-dimethyl-phenoxy)-acetyl]-piperazin-1-yl}-ethanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
57%	With dicyclohexyl-carbodiimide In chloroform for 14h; Ambient temperature;

Reference： [1]Chauhan, Jaya; Chauhan, J. S.; Gupta, P. P.; Srimal, R. C. [Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1993, vol. 32, # 2, p. 305 - 307]

6
[ 7356-41-4 ]
[ 4413-45-0 ]
6-(2,5-Dimethyl-phenoxymethyl)-3-(naphthalen-2-yloxymethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
55%	With trichlorophosphate for 5h; Heating;

Reference： [1]Holla, B. S.; Muralidharan, A.; Kalluraya, B. [Revue Roumaine de Chimie, 1994, vol. 39, # 1, p. 87 - 90]

7
[ 95-87-4 ]
[ 79-08-3 ]
[ 7356-41-4 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydride In tetrahydrofuran for 12h; Heating;

Reference： [1]Abraham, D. J.; Kennedy, P. E.; Mehanna, A. S.; Patwa, D. C.; Williams, F. L. [Journal of Medicinal Chemistry, 1984, vol. 27, # 8, p. 967 - 978]

8
[ 302-17-0 ]
[ 7356-41-4 ]
{3-[1-(3-carboxymethoxy-2,5-dimethyl-phenyl)-2,2,2-trichloro-ethyl]-2,5-dimethyl-phenoxy}-acetic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sulfuric acid

Reference： [1]Purohit; Shah [Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999, vol. 38, # 5, p. 618 - 622]

Yield	Reaction Conditions	Operation in experiment
	neben 2,5-Xylenol-methylether: 2,5-Xylenol, Betain, CaO, 190grad-255grad;
	2,5-Dimethyl-phenol, wss. NaOH, Chloressigsaeure, 100grad, 2 Std.;

10
[ 67-56-1 ]
[ 7356-41-4 ]
[ 95450-80-9 ]

Yield	Reaction Conditions	Operation in experiment
85%	With toluene-4-sulfonic acid at 25℃; for 2h;
	With toluene-4-sulfonic acid at 25℃; for 3h;

Reference： [1]Del Carmen Cruz, María; Tamariz, Joaquín [Tetrahedron, 2005, vol. 61, # 42, p. 10061 - 10072]
[2]Cruz, María Del Carmen; Tamariz, Joaquín [Tetrahedron Letters, 2004, vol. 45, # 11, p. 2377 - 2380]

11
[ 95-87-4 ]
[ 3926-62-3 ]
[ 7356-41-4 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide In water at 60℃; for 8h;

Reference： [1]Cruz, María Del Carmen; Tamariz, Joaquín [Tetrahedron Letters, 2004, vol. 45, # 11, p. 2377 - 2380]

12
[ 7356-41-4 ]
[ 713517-90-9 ]
5-(2,6-dichloro-benzyl)-1-(2,5-dimethyl-phenoxy)-9b-phenyl-5,9b-dihydro-1H-2a,5-diaza-benzo[a]cyclobuta[c]cycloheptene-2,4-dione [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
86%	With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine In dichloromethane at 0 - 20℃;

Reference： [1]Bolli, Martin H.; Marfurt, Judith; Grisostomi, Corinna; Boss, Christoph; Binkert, Christoph; Hess, Patrick; Treiber, Alexander; Thorin, Eric; Morrison, Keith; Buchmann, Stephan; Bur, Daniel; Ramuz, Henri; Clozel, Martine; Fischli, Walter; Weller, Thomas [Journal of Medicinal Chemistry, 2004, vol. 47, # 11, p. 2776 - 2795]

13
[ 7356-41-4 ]
methyl (Z)-3-dimethylamino-2-(2,5-dimethylphenoxy)propenoate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 85 percent / p-toluenesulfonic acid / 2 h / 25 °C 2: 65 percent / 24 h / 90 °C
	Multi-step reaction with 2 steps 1: p-toluenesulfonic acid / 3 h / 25 °C 2: 65 percent / 24 h / 90 °C

14
[ 7356-41-4 ]
rac-(SR)-[(5SR)-1-(2,6-dichlorobenzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,5-dimethylphenoxy)acetic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 86 percent / Et₃N; bis(2-oxo-3-oxazolidinyl)phosphinic chloride / CH₂Cl₂ / 0 - 20 °C 2: 91 percent / aq. LiOH / tetrahydrofuran; methanol / 45 - 60 °C

15
[ 7356-41-4 ]
2-(2,5-dimethyl-1H-pyrrol-1-yl)-5-((2,5-dimethylphenoxy)methyl)-1,3,4-thiadiazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: trichlorophosphate / 0.5 h / 75 °C 1.2: 4 h / Reflux 2.1: acetic acid / 1 h / Reflux

Reference： [1]Joshi, Shrinivas D.; More, Uttam A.; Koli, Deepshikha; Kulkarni, Manoj S.; Nadagouda, Mallikarjuna N.; Aminabhavi, Tejraj M. [Bioorganic Chemistry, 2015, vol. 59, p. 151 - 167]

16
[ 7356-41-4 ]
2-((2,5-dimethylphenoxy)methyl)-5-(1H-pyrrol-1-yl)-1,3,4-thiadiazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1.1: trichlorophosphate / 0.5 h / 75 °C 1.2: 4 h / Reflux 2.1: acetic acid / 1 h / Reflux

Reference： [1]Joshi, Shrinivas D.; More, Uttam A.; Koli, Deepshikha; Kulkarni, Manoj S.; Nadagouda, Mallikarjuna N.; Aminabhavi, Tejraj M. [Bioorganic Chemistry, 2015, vol. 59, p. 151 - 167]

17
[ 7356-41-4 ]
[ 79-19-6 ]
C₁₁H₁₃N₃OS [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Stage #1: 2,5-dimethylphenoxyacetic acid; thiosemicarbazide With trichlorophosphate at 75℃; for 0.5h; Stage #2: In water for 4h; Reflux;	General procedure for the preparation of 2-((phenoxy orsubstituted phenoxy)methyl/ethyl)-1,3,4-thiadiazol-5-amines (4a-qand 5a-q) General procedure: A mixture of benzoic acid (50 mmol), N-aminothiourea(50 mmol) and POCl3 (13 mL) was heated at 75 C for 0.5 h. Themixture was cooled to which water (10 mL) was added and thereaction mixture was refluxed for 4 h. The mixture was cooled and pH was adjusted to 8.0 by adding 50% sodium hydroxide solution.The separated solid was filtered and recrystallized from ethanolto give desired compounds.

Reference： [1]Joshi, Shrinivas D.; More, Uttam A.; Koli, Deepshikha; Kulkarni, Manoj S.; Nadagouda, Mallikarjuna N.; Aminabhavi, Tejraj M. [Bioorganic Chemistry, 2015, vol. 59, p. 151 - 167]

18
[ 7356-41-4 ]
tert-butyl 3-(4-[hydrazinyl(thioxo)acetyl]amino}phenyl)propanoate [ No CAS ]
3-{4-[({5-[(2,5-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}carbonyl)amino]phenyl}propanoic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
42%	Stage #1: 2,5-dimethylphenoxyacetic acid With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 0.5h; Inert atmosphere; Stage #2: tert-butyl 3-(4-[hydrazinyl(thioxo)acetyl]amino}phenyl)propanoate In dichloromethane at 20℃; for 16h; Inert atmosphere; Further stages;	General procedure for the preparation of compounds 4a-uand 5a-q General procedure: To a solution of the respective carboxylic acid (8a-u or 9,0.5 mmol) in DCM (4 mL) carbonyl-1,10-diimidazole (0.55 mmol,90 mg) was added and the mixture was stirred at r. t. for 30 min. Tothe resulting solution of the carboxylic acid imidazolide, respectivethiohydrazide (7 or 10a-q) was added and the reaction mixturewasstirred at r. t. for 16 h. The solvent was removed in vacuo, the residuewasdissolved in glacial acetic acid (3 mL) and the solutionwasheated at reflux for 30 min. It was then cooled down to r. t., pouredinto water (50 mL), the resulting precipitate was collected byfiltration and dried in vacuo. It was then combined with 4 M solutionof HCl in 1,4-dioxane (5 mL); the mixture was stirred at r. t.for 16 h and poured into water (50 mL). The precipitate wascollected by filtration, washed with water and air-dried to providethe title compounds in yields indicated.

Reference： [1]Krasavin, Mikhail; Lukin, Alexei; Bakholdina, Anna; Zhurilo, Nikolay; Onopchenko, Oleksandra; Borysko, Petro; Zozulya, Sergey; Moore, Daniel; Tikhonova, Irina G. [European Journal of Medicinal Chemistry, 2017, vol. 140, p. 229 - 238]

19
[ 7356-41-4 ]
[ 518-28-5 ]
(5S,5aR,8aR,9R)-8-oxo-9-(3,4,5-trimethoxyphenyl)-5,5a,7,8,8a,9-hexahydrofuro[2’,3’:6,7]naphtho[2,3-d][1,3]dioxol-5-yl 2-(2,5-dimethylphenoxy)acetate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
75%	With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 12h;	General procedure for preparation of compoundsM1-M16 General procedure: Fibiric acids derivatives L1-L16 (0.015 mol), podophyllotoxin(0.01 mol), 4-dimethyaminopyridine (DMAP) (0.001mol) and N,N-dicyclohexylcarbodiimide (DCC) (0.02 mol)were dissolved in dichloromethane (30 mL) and stirred for12 h at room temperature. Then, a proper amount of silicagel were added and the solvent was condensed by vacuumconcentration. Finally, the target compounds were collectedby column chromatography (V(acetone): V(dichloromethane)= 1: 50). Chemical structures of the targetcompounds (M1-M16) were shown in Fig. 2. All the targetcompounds were reported for the first time.

Reference： [1]Hu, Cui; Zhu, Xiang; Wang, Gu-Hao; Wu, Xun; Han, Hong-Wei; Lu, Gui-Hua; Qi, Jin-Liang; Pang, Yan-Jun; Yang, Rong-Wu; Wang, Xiao-Ming; Yang, Yong-Hua [Medicinal Chemistry Research, 2018, vol. 27, # 2, p. 351 - 365]

20
[ 95-87-4 ]
[ 59956-48-8 ]
[ 7356-41-4 ]

Yield	Reaction Conditions	Operation in experiment
32%	Stage #1: 2,5-Dimethylphenol; isobutyl 2-bromoacetate With potassium carbonate In acetonitrile at 82℃; for 12h; Sealed tube; Inert atmosphere; Stage #2: With sodium hydroxide In acetonitrile at 100℃; for 24h; Sealed tube; Inert atmosphere;	4.3. General procedure for synthesis of 4a-d General procedure: To a 6 dram vial was added esters 3a-d, followed byK2CO3(2.5eq) 2,5-dimethylphenol (1 eq), and MeCN (2 mL)and the reactionheated to 82 C for 12 h. After cooling to 25 C,1MNaOH (2 mL)wasadded and the reaction heated to 100 C for 24 h. The resulting mixture was then partitioned between EtOAc (5 mL) and brine(10 mL) and the organic phase dried withMgSO4and evaporated byrotary evaporation. The resulting residue was purified by silicachromatography (10e20% EtOAc in hexanes).

Reference： [1]Baker, Hannah; Ferreira, Liam D.; Gayler, Kevin M.; Kane, Robert R.; Karunananthan, Johann W.; Kostyo, Jessica H.; Martin, Emil; Mattke, Jordan; Nguyen, Harold; Plunk, Michael A.; Quintana, Jeremy M.; Sharina, Iraida; Shuda, Mina; Stinchcomb, Alexandra L. [European Journal of Medicinal Chemistry, 2021, vol. 224]

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Prevention
Code	Phrase
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P230	Keep wetted
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P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
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P321
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P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 7356-41-4 ] {[proInfo.proName]}

Quality Control of [ 7356-41-4 ]

Related Doc. of [ 7356-41-4 ]

Product Details of [ 7356-41-4 ]

Calculated chemistry of [ 7356-41-4 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 7356-41-4 ]

Application In Synthesis of [ 7356-41-4 ]

[ 7356-41-4 ] Synthesis Path-Downstream 1~20

Related Functional Groups of [ 7356-41-4 ]

Aryls

Ethers

Carboxylic Acids

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 7356-41-4 ]