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Chemical Structure| 7423-42-9 Chemical Structure| 7423-42-9

Structure of 7423-42-9

Chemical Structure| 7423-42-9

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Product Citations

Product Citations

Han, Xuexiang ; Xu, Ying ; Ricciardi, Adele ; Xu, Junchao ; Palanki, Rohan ; Chowdhary, Vivek , et al.

Abstract: mRNA-based gene editing therapeutics offer the potential to permanently cure diseases but are hindered by suboptimal delivery platforms. Here, we devise a robust combinatorial chemistry for plug-and-play assembly of diverse biodegradable ionizable lipids and identify a lead candidate that produces superior lipid nanoparticles for various gene editing tools delivery in vivo. Our study highlights the utility of this synthetic approach and the generality of this platform for potent in vivo gene editing.

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Product Details of [ 7423-42-9 ]

CAS No. :7423-42-9
Formula : C12H20O4
M.W : 228.28
SMILES Code : O=C(OCC(CC)CCCC)/C=C\C(O)=O
MDL No. :MFCD00080510
InChI Key :IQBLWPLYPNOTJC-FPLPWBNLSA-N
Pubchem ID :5365056

Safety of [ 7423-42-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H373-H317-H412-H302-H315-H318-H334
Precautionary Statements:P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501-P261-P285-P304+P341-P342+P311-P501-P260-P314-P501-P273-P501
 

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