[ CAS No. 7494-45-3 ] {[proInfo.proName]}

Name: 7494-45-3|1,2-Dichloro-4-methyl-5-nitrobenzene|95%
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Quality Control of [ 7494-45-3 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 7494-45-3 ]

Product Details of [ 7494-45-3 ]

CAS No. :	7494-45-3	MDL No. :	MFCD01109847
Formula :	C₇H₅Cl₂NO₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	AOTWCYSQDSKAQT-UHFFFAOYSA-N
M.W :	206.03	Pubchem ID :	343795
Synonyms :

Safety of [ 7494-45-3 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P280-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 7494-45-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 7494-45-3 ]
Downstream synthetic route of [ 7494-45-3 ]

[ 7494-45-3 ] Synthesis Path-Upstream 1~7

1
[ 95-75-0 ]
[ 7494-45-3 ]

Yield	Reaction Conditions	Operation in experiment
98%	at 0 - 20℃; for 2 h;	Fuming nitric acid (40 mL) was added dropwise to 0 °C solution of 1,2-dichloro-4-methylbenzene (20 g, 124.20 mmol), and the resulting solution was stirred for 2 h at room temperature. The reaction mixture was then slowly poured into 200 mL of water/ice. The solids were collected by filtration and dried under vacuum to afford l,2-dichloro-4-methyl-5- nitrobenzene (25.2 g, 98percent) as a yellow solid. 1H- MR: (DMSO, 300 MHz) δ (ppm): 8.39 (s, 1H), 7.96 (s, 1H), 2.48 (s, 3H).
92%	With nitric acid In water	Step A 4,5-Dichloro-2-methyl-nitrobenzene 5 To stirred 3,4-dichloro-toluene 4 (10.0 g, 62.2 mmol) at 0° C. was slowly added fuming nitric acid (20.0 mL). The mixture was stirred for 2 hrs at RT, then water added (200 mL) and the reaction mixture filtered. The filtrate was purified by silica gel chromatography using 5percent ethyl acetate in hexanes to give the title compound 11.7 g (92percent). ¹H NMR (400 MHz, CDCl₃) δ8.14 (s, 1 H, Ar), 7.47 (s, 1 H, Ar), 2.59 (s, 3 H, CH₃).

Reference： [1] Patent: WO2018/75959, 2018, A1, . Location in patent: Paragraph 0639-0640
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 10, p. 1568 - 1573
[3] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 4, p. 1966 - 1982
[4] Tetrahedron, 1998, vol. 54, # 12, p. 2953 - 2966
[5] Journal of the Chemical Society, 1902, vol. 81, p. 1349
[6] Journal of the Chemical Society, 1901, vol. 79, p. 1133
[7] Patent: US6376530, 2002, B1,
[8] Patent: WO2007/14054, 2007, A2, . Location in patent: Page/Page column 33-34

2
[ 89-69-0 ]
[ 996-82-7 ]
[ 7494-45-3 ]
[ 7149-76-0 ]

Reference： [1] Synthesis, 2000, # 12, p. 1659 - 1661

3
[ 70343-10-1 ]
[ 7494-45-3 ]

Reference： [1] Journal of Scientific and Industrial Research, 1951, vol. 10 B, p. 140,143

4
[ 70902-72-6 ]
[ 7494-45-3 ]

Reference： [1] Journal of the Chemical Society, 1925, vol. 127, p. 2348
[2] Journal of the Chemical Society, 1925, vol. 127, p. 2348

5
[ 7494-45-3 ]
[ 4637-24-5 ]
[ 121859-57-2 ]

Reference： [1] RSC Advances, 2014, vol. 4, # 9, p. 4672 - 4675
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 10, p. 1598 - 1612

6
[ 7494-45-3 ]
[ 121859-57-2 ]

Reference： [1] Patent: WO2018/75959, 2018, A1,

7
[ 7494-45-3 ]
[ 124691-76-5 ]

Reference： [1] Patent: WO2013/30138, 2013, A1,

[ 7494-45-3 ] Synthesis Path-Downstream 1~15

1
[ 95-75-0 ]
[ 7494-45-3 ]

Yield	Reaction Conditions	Operation in experiment
98%	With nitric acid; at 0 - 20℃; for 2h;	Fuming nitric acid (40 mL) was added dropwise to 0 C solution of <strong>[95-75-0]1,2-dichloro-4-methylbenzene</strong> (20 g, 124.20 mmol), and the resulting solution was stirred for 2 h at room temperature. The reaction mixture was then slowly poured into 200 mL of water/ice. The solids were collected by filtration and dried under vacuum to afford l,2-dichloro-4-methyl-5- nitrobenzene (25.2 g, 98%) as a yellow solid. 1H- MR: (DMSO, 300 MHz) delta (ppm): 8.39 (s, 1H), 7.96 (s, 1H), 2.48 (s, 3H).
11.7 g (92%)	With nitric acid; In water;	Step A 4,5-Dichloro-2-methyl-nitrobenzene 5 To stirred <strong>[95-75-0]3,4-dichloro-toluene</strong> 4 (10.0 g, 62.2 mmol) at 0 C. was slowly added fuming nitric acid (20.0 mL). The mixture was stirred for 2 hrs at RT, then water added (200 mL) and the reaction mixture filtered. The filtrate was purified by silica gel chromatography using 5% ethyl acetate in hexanes to give the title compound 11.7 g (92%). 1H NMR (400 MHz, CDCl3) delta8.14 (s, 1 H, Ar), 7.47 (s, 1 H, Ar), 2.59 (s, 3 H, CH3).
	With sulfuric acid; nitric acid; at 0 - 20℃; for 0.166667h;	Nitric acid was added slowly to a mixture of 1 ,2-dichloro-4-methylbenzene (10 g) in sulfuric acid at 0 C, keeping the temperature below 100C. The mixture was allowed to warm to room temperature, stirred for 10 minutes, poured over ice (250 g) and stirred for 10 further minutes. The solid was filtered, washed with water (50 mL) and dissolved in EPO <DP n="35"/>DCM (150 mL). The resulting solution was washed with water (120 ml_) and brine (100 mL), dried over magnesium sulfate and concentrated. To the resulting solid at 150 0C was added bromine (3.4 mL). The mixture stirred for 30 minutes, poured into hexane (50 mL) and stirred for a further 10 minutes. The solution was filtered and the filter-pad washed with hexanes. The filtrates were combined and washed with water (2 x 100 mL), dried over magnesium sulfate and concentrated to give the crude title compound (8.2 g). 1H NMR (CDCI3) delta 8.20 (s, 1 H), 7.69 (s, 1 H), 4.77 (s, 2H)

Reference： [1]Patent: WO2018/75959,2018,A1 .Location in patent: Paragraph 0639-0640
[2]Journal of Medicinal Chemistry,1998,vol. 41,p. 1568 - 1573
[3]Bioorganic and Medicinal Chemistry,2008,vol. 16,p. 1966 - 1982
[4]Tetrahedron,1998,vol. 54,p. 2953 - 2966
[5]Journal of the Chemical Society,1902,vol. 81,p. 1349
[6]Journal of the Chemical Society,1901,vol. 79,p. 1133
[7]Patent: US6376530,2002,B1
[8]Patent: WO2007/14054,2007,A2 .Location in patent: Page/Page column 33-34

2
[ 7494-45-3 ]
[ 2387-08-8 ]

Yield	Reaction Conditions	Operation in experiment
99%	With iron; ammonium chloride In tetrahydrofuran; methanol; water at 100℃; for 3h;	67.1 Step 14,5-Dichloro-2-methylanilin Example 67.2-(5 ,6-Dichloro- 1 -methyl- 1 H-indazol-3 -yl)-5H-pyrrolo [2,3 -b]pyrazine-7-carboxylic acid [(R)-2- (4-cyano-piperidin-l -yl)-l -cyclopropyl-2-oxo-ethyl]-amideStep 14,5-Dichloro-2-methylanilinTo a partial suspension of l ,2-dichloro-4-methyl-5-nitrobenzene (2.0 g, 9.71 mmol) in MeOH (25 ml), water (25 ml), and THF (10 ml) was added NH4C1 (5.19 g, 97.1 mmol) followed by iron powder (2.71 g, 48.5 mmol). The heterogeneous reaction mixture was heated at 100°C for 3 h then cooled to room temperature and filtered over a Buchner funnel, rinsing with MeOH. The filtrate was diluted with water and saturated aqueous NaHC03 then extracted with CH2CI2 (3x). The combined organics were dried over MgS04 and concentrated to afford 1.69 g (99%) of 4,5- dichloro-2-methylaniline as a white solid. 1H NMR (CDC13, 300 MHz): ? (ppm) 7.10 (s, 1H), 6.75 (s, 1H), 3.74 (br. s., 2H), 2.12 (s, 3H).
98%	With hydrazine hydrate
88%	With hydrogenchloride; tin(ll) chloride In ethanol at 20℃; for 17h;

	bei der Reduktion;
2.4 g (56%)	In titanium(III) chloride	7.B 4,5-Dichloro-2-methyl-phenylamine 6 Step B 4,5-Dichloro-2-methyl-phenylamine 6 4,5-Dichloro-2-methyl-nitrobenzene 5 (5.0 g, 24.3 mmol) was heated at 100° C. in titanium trichloride (30% in aqueous hdyrochloric acid, 25 mL) for 2 hrs., cooled to RT, the reaction solution was basified to pH 8 with 50% aqueous sodium hydroxide, then extracted with ethyl acetate. The ethyl acetate layer was washed with water, brine, dried over sodium sulfate, filtered and concentrated. The residue was purified by silica gel chromatography using 10% ethyl acetate in hexanes to give 2.4 g (56%) of the title product. 1H NMR (400 MHz, CDCl3) δ7.09 (s, 1 H, Ar), 6.74 (s, 1 H, Ar), 3.63 (s, 2 H, NH2), 2.10 (s, 3H, CH3).

Reference： [1]Current Patent Assignee: ROCHE HOLDING AG - WO2013/30138, 2013, A1 Location in patent: Page/Page column 187; 188
[2]De Lang, Robbert-Jan; Van Hooijdonk, Marcel J.C.M.; Brandsma, Lambert; Kramer, Hester; Seinen, Willem [Tetrahedron, 1998, vol. 54, # 12, p. 2953 - 2966]
[3]Shimada, Itsuro; Maeno, Kyoichi; Kazuta, Ken-ichi; Kubota, Hideki; Kimizuka, Tetsuya; Kimura, Yasuharu; Hatanaka, Ken-ichi; Naitou, Yuki; Wanibuchi, Fumikazu; Sakamoto, Shuichi; Tsukamoto, Shin-ichi [Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 4, p. 1966 - 1982]
[4]Cohen; Dakin [Journal of the Chemical Society, 1902, vol. 81, p. 1335][Journal of the Chemical Society, 1906, vol. 89, p. 1454]
[5]Cohen; Dakin [Journal of the Chemical Society, 1902, vol. 81, p. 1335][Journal of the Chemical Society, 1906, vol. 89, p. 1454]
[6]Current Patent Assignee: MERCK & CO INC - US6376530, 2002, B1

3
[ 7494-45-3 ]
[ 2011-09-8 ]

Yield	Reaction Conditions	Operation in experiment
	With chromium(VI) oxide; sulfuric acid at -15℃;

Reference： [1]Ruggli; Zaeslin [Helvetica Chimica Acta, 1936, vol. 19, p. 434,437]

4
[ 7494-45-3 ]
[ 4637-24-5 ]
[ 121859-57-2 ]

Reference： [1]RSC Advances,2014,vol. 4,p. 4672 - 4675
[2]Journal of Medicinal Chemistry,1998,vol. 41,p. 1598 - 1612

5
[ 7664-93-9 ]
[ 7494-45-3 ]
[ 2011-09-8 ]

Yield	Reaction Conditions	Operation in experiment
	at -15℃;

Reference： [1]Ruggli; Zaeslin [Helvetica Chimica Acta, 1936, vol. 19, p. 434,437]

6
[ 7494-45-3 ]
[ 50-82-8 ]

Reference： [1]Journal of the Chemical Society,1902,vol. 81,p. 1335
Journal of the Chemical Society,1906,vol. 89,p. 1454

7
[ 7494-45-3 ]
[ 75279-53-7 ]
[ 1093097-87-0 ]

Yield	Reaction Conditions	Operation in experiment
		A solution of 4-chloro-2-fluorobenzeneacetonitrile (0.059 mol) in anhydrous DMF (150 ml) was chilled on an ice-bath. t-BuOK (0.118 mol) was added under nitrogen and the resulting mixture was stirred for 30 minutes. l,2-Dichloro-4-methyl-5- nitrobenzene (0.059 mol) was added and the reaction mixture was stirred for 1 hour at 00C. The mixture was allowed to warm to room temperature for 1 hour and then cooled to 00C. A solution of hydrogen peroxide in water (30%) (17.8 ml) was added and air was bubbled through the solution overnight. The obtained mixture was slowly added dropwise to IN HCl (750 ml) and after stirring in ice-cold DIPE, the resulting precipitate was filtered off, yielding 5.83 g of intermediate (1).

Reference： [1]Patent: WO2008/152081,2008,A2 .Location in patent: Page/Page column 9

8
[ 7494-45-3 ]
[ 124691-76-5 ]

Reference： [1]Patent: WO2013/30138,2013,A1

9
[ 7494-45-3 ]
[ 1426421-76-2 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1.1: ammonium chloride; iron / tetrahydrofuran; water; methanol / 3 h / 100 °C 2.1: acetic anhydride / chloroform / 0 - 20 °C 2.2: Reflux 3.1: iodine; potassium hydroxide / N,N-dimethyl-formamide / 0.75 h / 20 °C

Reference： [1]Current Patent Assignee: ROCHE HOLDING AG - WO2013/30138, 2013, A1

10
[ 7494-45-3 ]
[ 1426421-77-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: ammonium chloride; iron / tetrahydrofuran; water; methanol / 3 h / 100 °C 2.1: acetic anhydride / chloroform / 0 - 20 °C 2.2: Reflux 3.1: iodine; potassium hydroxide / N,N-dimethyl-formamide / 0.75 h / 20 °C 4.1: potassium <i>tert</i>-butylate / tetrahydrofuran / 0.5 h / 0 °C 4.2: 0 - 20 °C

Reference： [1]Current Patent Assignee: ROCHE HOLDING AG - WO2013/30138, 2013, A1

11
[ 402-45-9 ]
[ 7494-45-3 ]
1-chloro-4-methyl-5-nitro-2-[4-(trifluoromethyl)phenoxy]benzene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
78%	With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 2h;	First, into a 100-mL round-bottom flask, was placed 1,2-dichloro-4-methyl-5-nitrobenzene (1 g, 4.85 mmol, 1.00 equiv), N,N-dimethylformamide (20 mL), potassium carbonate (2 g, 14.47 mmol, 3.00 equiv), 4-(trifluoromethyl)phenol (786 mg, 4.85 mmol, 1.00 equiv). The resulting solution was stirred for 2 h at 100° C. in an oil bath. The resulting solution was diluted with 20 mL of H2O. The resulting solution was extracted with 3×20 mL of ethyl acetate and the organic layers combined. The resulting mixture was washed with 3×20 mL of brine. The organic phase was dried over anhydrous sodium sulfate and concentrated under vacuum. This resulted in 1.2 g (78%) of 1-chloro-4-methyl-5-nitro-2-[4-(trifluoromethyl)phenyl]benzene as a brown solid.

Reference： [1]Current Patent Assignee: C.H. Boehringer Sohn AG & Co. KG - US2015/366198, 2015, A1 Location in patent: Paragraph 0223

12
[ 7494-45-3 ]
[ 121859-57-2 ]

Reference： [1]Patent: WO2018/75959,2018,A1

13
[ 7494-45-3 ]
[ 288-36-8 ]
2-(2-chloro-5-methyl-4-nitrophenyl)-2H-1,2,3-triazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
15.5%	With potassium fluoride; potassium carbonate; In acetonitrile; at 80℃;	The mixture of 1,2-dichloro-4-methyl-5-nitrobenzene (1.0 g, 4.85 mmol), 2H-1,2,3-triazole (0.32 mL, 5.83 mmol), potassium carbonate (2.01 g, 14.56 mmol) and potassium fluoride (226 mg, 3.88 mmol) in acetonitrile (10 mL) was stirred at 80 C. overnight. The solid was collected by filtration and then was washed with 50 mL ethyl acetate. The solvent was concentrated to give the crude product as a yellow solid. The crude product was purified by column chromatography over silica gel (petroleum ether/ethyl acetate=100:0 to 50:50). The solvent was concentrated to afford the product as a white solid (180 mg, 15.5% yield). 1H NMR (400 MHz, CHLOROFORM-d) delta ppm 7.69 (s, 1H), 7.64 (d, J=1.00 Hz, 1H), 7.40 (d, J=1.25 Hz, 1H), 7.21 (s, 1H) 2.11 (s, 3H).

Reference： [1]Patent: US2018/170909,2018,A1 .Location in patent: Paragraph 1803; 1804

14
[ 7494-45-3 ]
[ 243139-71-1 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1.1: potassium fluoride; tetrabutylammomium bromide / sulfolane / 2 h / 75 - 80 °C 2.1: hydrogen / methanol / 3 h / 55 - 60 °C / 60006 Torr / Sealed tube 3.1: sodium nitrite; tetrafluoroboric acid / water / -40 - 25 °C 3.2: 2 h / 100 - 180 °C / Pyrolysis 4.1: 2,2'-azobis(isobutyronitrile); hydrogenchloride / water / 3 h / 110 °C

Reference： [1]Current Patent Assignee: HANGZHOU ZHENZHI BIOLOGICAL TECH - CN112851493, 2021, A

15
[ 7494-45-3 ]
[ 220141-74-2 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 5 steps 1.1: potassium fluoride; tetrabutylammomium bromide / sulfolane / 2 h / 75 - 80 °C 2.1: hydrogen / methanol / 3 h / 55 - 60 °C / 60006 Torr / Sealed tube 3.1: sodium nitrite; tetrafluoroboric acid / water / -40 - 25 °C 3.2: 2 h / 100 - 180 °C / Pyrolysis 4.1: 2,2'-azobis(isobutyronitrile); hydrogenchloride / water / 3 h / 110 °C 5.1: 2,2'-azobis(isobutyronitrile) / dimethyl sulfoxide / 5 h / 70 °C

Reference： [1]Current Patent Assignee: HANGZHOU ZHENZHI BIOLOGICAL TECH - CN112851493, 2021, A

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Ghs Precautionary Statements

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P101	If medical advice is needed,have product container or label at hand.
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P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
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P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
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P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
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P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 7494-45-3 ] {[proInfo.proName]}

Quality Control of [ 7494-45-3 ]

Related Doc. of [ 7494-45-3 ]

Product Details of [ 7494-45-3 ]

Safety of [ 7494-45-3 ]

Application In Synthesis of [ 7494-45-3 ]

[ 7494-45-3 ] Synthesis Path-Upstream 1~7

[ 7494-45-3 ] Synthesis Path-Downstream 1~15

Related Functional Groups of [ 7494-45-3 ]

Aryls

Chlorides

Nitroes

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 7494-45-3 ]