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Chemical Structure| 7497-60-1 Chemical Structure| 7497-60-1

Structure of 7497-60-1

Chemical Structure| 7497-60-1

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Product Details of [ 7497-60-1 ]

CAS No. :7497-60-1
Formula : C13H8ClNO3
M.W : 261.66
SMILES Code : O=C(C1=CC=C(Cl)C=C1)C2=CC=C([N+]([O-])=O)C=C2
MDL No. :MFCD00047743
InChI Key :CLFRUWPJQKSRRT-UHFFFAOYSA-N
Pubchem ID :347771

Safety of [ 7497-60-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 7497-60-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7497-60-1 ]

[ 7497-60-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 622-32-2 ]
  • [ 7497-60-1 ]
  • [ 42019-78-3 ]
YieldReaction ConditionsOperation in experiment
In dimethyl sulfoxide; Preparation of 4'-chloro-4-hydroxybenzophenone 250 cc of DMSO and 4.8 g sodium hydride are placed in a 500 cc flask and heated at 70° C for 1 hour, by which time the solution has become clear. A solution of 24.2 g (0.2 mole) of benzaldoxime in 100 cc of DMSO is then added drop by drop. The solution is maintained at 70° C for 1 hour, then allowed to cool to 15° C. A solution of 26 g (0.1 mole) of 4'-chloro-4-nitrobenzophenone in 150 cc of DMSO is then added. The reaction mixture is stirred for 20 hours at ambient temperature and then poured into acidulated water. The mixture is extracted with ether and then with ether containing 2N caustic soda. On acidification the product is precipitated. Yield 15 g (65percent). Melting point 178° C.
 

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