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Chemical Structure| 75677-02-0 Chemical Structure| 75677-02-0

Structure of 75677-02-0

Chemical Structure| 75677-02-0

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Product Details of [ 75677-02-0 ]

CAS No. :75677-02-0
Formula : C9H9ClO
M.W : 168.62
SMILES Code : O=CCCC1=CC=C(Cl)C=C1
MDL No. :MFCD07772912
InChI Key :UXIFTAZOVKVCBX-UHFFFAOYSA-N
Pubchem ID :11535622

Safety of [ 75677-02-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 75677-02-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 75677-02-0 ]

[ 75677-02-0 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 75677-02-0 ]
  • [ 392338-15-7 ]
  • [ 762285-62-1 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In DMF (N,N-dimethyl-formamide); at 70℃; for 20h; Amine 20c (17.4 g, 86.9 MMOL,) compound 20a (30.8 g, 86. 7 MMOL,) and TEA (48.6 mL, 0. 35 mol) were dissolved in DMF (110 mL) and heated (70 C) in an oil-bath (20 hr.) After removal of solvent under vacuum, the residual mixture was diluted with DCM : I-PROH (3: 1,1600 mL, ) washed 3 times with aliquots (200 mL) OF NAOH/H20 (0.5 N, ) washed once with brine (200 mL, ) dried over MGS04, filtered and concentrated. To the residue was added ether (50 mL, ) and this mixture was kept at 4 C overnight prior to filtration and washing with cold ether to give 20d (19. 25 g. ) The mother liquor was concentrated and purified via flash chromatography to afford a second batch of crystals. The combined yield of 20d was 24.8 g. LC-MS: 417.1 (MH+).
  • 2
  • [ 75677-02-0 ]
  • [ 2605-68-7 ]
  • (E)-methyl 5-(4-chlorophenyl)-2-methylpent-2-enoate [ No CAS ]
  • 3
  • [ 7724-12-1 ]
  • [ 75677-02-0 ]
  • 6-[3-(4-chlorophenyl)propylamino]-2-cyanobenzothiazole [ No CAS ]
 

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