[ CAS No. 7664-66-6 ]

Name: 7664-66-6|4-Isopropoxyaniline|97%
Brand: Ambeed
SKU: A210878
Price: 6.0 USD
Availability: InStock
Rating: 96 (27 reviews)

{[proInfo.proName]} ,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

DV 2D 3D

Structure of 7664-66-6 * Storage: {[proInfo.prStorage]}

Cart0 Bulk Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 88K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 7664-66-6 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 7664-66-6 ]

SDS

Alternatived Products of [ 7664-66-6 ]

Product Details of [ 7664-66-6 ]

CAS No. :	7664-66-6	MDL No. :	MFCD00059188
Formula :	C₉H₁₃NO	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	-
M.W :	151.21 g/mol	Pubchem ID :	82112
Synonyms :

Safety of [ 7664-66-6 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 7664-66-6 ]

Upstream synthesis route of [ 7664-66-6 ]
Downstream synthetic route of [ 7664-66-6 ]

[ 7664-66-6 ] Synthesis Path-Upstream 1~17

1
[ 123-30-8 ]
[ 75-26-3 ]
[ 7664-66-6 ]

Yield	Reaction Conditions	Operation in experiment
62%	With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 24 h;	General procedure: These syntheses were carried out in one step as per De Marco et al. [24] Aminophenol (92 mmol) and a suspension of NaH in mineral oil (275 mmol NaH) were suspended in dry DMF (100 mL). The corresponding alkylbromide (137 mmol) was added dropwise and the mixture was then stirred for 24 h at room temperature. The reaction was quenched by adding 400 mL of distilled water and the aqueous layer was extracted with 3 × 150 mL of ethyl acetate. Collected organic layers were dried over anhydrous Na₂SO₄ and concentrated in vacuo. Pure product was obtained by distillation under reduced pressure.

Reference： [1] Molecules, 2015, vol. 20, # 6, p. 9767 - 9787
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 20, p. 4898 - 4908
[3] Molecules, 2018, vol. 23, # 7,

2
[ 683-60-3 ]
[ 106-47-8 ]
[ 7664-66-6 ]

Yield	Reaction Conditions	Operation in experiment
71%	With hemicucurbituril supported [Bmim]Cl In toluene for 10 h; Reflux	General procedure: A mixture of aryl halide (1 mmol) and sodium alkoxide(3.0 mmol) was refluxed in the presence of 200 mg ofHmCucSILP catalyst in toluene (5 mL) for an appropriatetime as indicated in Table 2. After completion of thereaction, the reaction mixture was filtered and solvent wasevaporated in vacuo to give the crude product, which waspurified by column chromatography over silica gel usinghexane/EtOAc as the eluent.

Reference： [1] Catalysis Letters, 2016, vol. 146, # 12, p. 2485 - 2494

3
[ 683-60-3 ]
[ 106-40-1 ]
[ 7664-66-6 ]

Yield	Reaction Conditions	Operation in experiment
73%	With hemicucurbituril supported [Bmim]Cl In toluene for 9 h; Reflux	General procedure: A mixture of aryl halide (1 mmol) and sodium alkoxide(3.0 mmol) was refluxed in the presence of 200 mg ofHmCucSILP catalyst in toluene (5 mL) for an appropriatetime as indicated in Table 2. After completion of thereaction, the reaction mixture was filtered and solvent wasevaporated in vacuo to give the crude product, which waspurified by column chromatography over silica gel usinghexane/EtOAc as the eluent.

Reference： [1] Catalysis Letters, 2016, vol. 146, # 12, p. 2485 - 2494

4
[ 683-60-3 ]
[ 540-37-4 ]
[ 7664-66-6 ]

Yield	Reaction Conditions	Operation in experiment
74%	With hemicucurbituril supported [Bmim]Cl In toluene for 10 h; Reflux	General procedure: A mixture of aryl halide (1 mmol) and sodium alkoxide(3.0 mmol) was refluxed in the presence of 200 mg ofHmCucSILP catalyst in toluene (5 mL) for an appropriatetime as indicated in Table 2. After completion of thereaction, the reaction mixture was filtered and solvent wasevaporated in vacuo to give the crude product, which waspurified by column chromatography over silica gel usinghexane/EtOAc as the eluent.

Reference： [1] Catalysis Letters, 2016, vol. 146, # 12, p. 2485 - 2494

5
[ 26455-31-2 ]
[ 7664-66-6 ]

Reference： [1] Org.Synth.Coll.Vol.III<1955>140,
[2] Patent: WO2013/149997, 2013, A1, . Location in patent: Page/Page column 43

6
[ 73010-54-5 ]
[ 7664-66-6 ]
[ 104-94-9 ]