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Chemical Structure| 774-05-0 Chemical Structure| 774-05-0

Structure of 774-05-0

Chemical Structure| 774-05-0

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Product Details of [ 774-05-0 ]

CAS No. :774-05-0
Formula : C10H16O3
M.W : 184.23
SMILES Code : O=C(C1C(CCCCC1)=O)OCC
MDL No. :MFCD00604086
InChI Key :MKRBAWHVHOVBOQ-UHFFFAOYSA-N
Pubchem ID :279795

Safety of [ 774-05-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 774-05-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 774-05-0 ]

[ 774-05-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 774-05-0 ]
  • [ 6100-60-3 ]
  • [ 401479-60-5 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; trifluoroacetic acid; at 0 - 20℃; for 3h; General procedure: 4-Methoxyresorcinol or 4-chlororesorcinol or hydroquinone (11.0 mmol) was dissolved in hot ethyl 2-oxocycloheptanecarboxylate (3a) or ethyl 2-oxocyclooctanecarboxylate (3b) (11.0 mmol). This mixture was then stirred in an ice bath, and a mixture of trifluoroacetic acid (1.7 mL, 22.0 mmol) and conc. sulfuric acid (2.2 mL, 22.0 mmol) was added thereto dropwise at a rate such that the reaction temperature was kept below 10C (about 30 min), and further stirred at room temperature for 3 h. It was further quenched cautiously with ice-water. The mixture was partitioned between water and ethyl acetate, the aqueous layer was extracted with ethyl acetate three times, and the combined organic layer extracts were then washed with saline (3 × 25 mL) and dried over anhydrous sodium sulfate. The crude product was used in the next step without further purification.
 

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