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Chemical Structure| 778641-02-4 Chemical Structure| 778641-02-4

Structure of 778641-02-4

Chemical Structure| 778641-02-4

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Product Details of [ 778641-02-4 ]

CAS No. :778641-02-4
Formula : C8H6Br2
M.W : 261.94
SMILES Code : Br/C=C/C1=CC=C(Br)C=C1
MDL No. :MFCD07369177

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Application In Synthesis of [ 778641-02-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 778641-02-4 ]

[ 778641-02-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 778641-02-4 ]
  • [ 100-63-0 ]
  • [ 13667-12-4 ]
YieldReaction ConditionsOperation in experiment
96.2% With dmap; zirconocene dichloride; dichloro(1,2-bis(diphenylphosphino)ethane)cobalt(II); 1-(1-ferrocenylethyl)-3-isopropyl-imidazolium iodide salt; In 1,4-dioxane; at 75℃; for 2.5h;Inert atmosphere; Under a nitrogen atmosphere and room temperature, to the proper amount of organic solvent (in mass ratio of 8:1 of the 1,4-dioxane and 1-butyl-3-methyl imidazole trifluoroacetic acid salt mixture) in, adding 100mmol compounds represented by the following general formula (I) compound, 120mmol aboving (II) compound, 14mmol catalyst [1,2-bis (mortars; concrete ; artificial stone) ethane] two chlorine cobalt, 45mmol alkali dimethylamino pyridine (DMPA) and 12mmol adjuvant (for 9mmol double (cyclopentadienyl) zirconium dichloride and 3mmol1 - (1-ferrocene amido ethyl) - 3-isopropyl-1-imidazole Iodized salt mixture), then heating to 75 C, and stirring reaction at this temperature 2.5 hours. After the reaction, filtration, adjusting the pH value of the filtrate to neutral, and adding de-ionized water, fully stirring, then adding chloroform for the oscillation extraction, layering, the organic phase is separated, dried anhydrous sodium sulfate, concentrated under reduced pressure, the resulting residue over silica gel column chromatography, to volume ratio of 4:1 of the mixed solution of acetone and ethyl acetate eluviation, so as to obtain the compound of formula (III), the yield is 96.2%.
 

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