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Chemical Structure| 78461-64-0 Chemical Structure| 78461-64-0

Structure of 78461-64-0

Chemical Structure| 78461-64-0

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Product Details of [ 78461-64-0 ]

CAS No. :78461-64-0
Formula : C12H20O5
M.W : 244.28
SMILES Code : O=C(C(CC1)(CO)CCC21OCCO2)OCC
MDL No. :MFCD16036673

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Application In Synthesis of [ 78461-64-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 78461-64-0 ]

[ 78461-64-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1120-95-2 ]
  • [ 78461-64-0 ]
  • ethyl 8-((pyridazin-3-yloxy)methyl)-1,4-dioxaspiro[4.5]decane-8-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium tert-butylate; In N,N-dimethyl-formamide; at 0 - 20℃;Inert atmosphere; To the solution of ethyl 8-(hydroxymethyl)- 1 ,4-dioxaspiro[4 .5jdecane-8-carboxylate (300 mg, 1.23 mmol) in DMF (6 mL) at 0 °C was added potassium tert-butoxide (1.84 mL, 1.84 mmol) followed by <strong>[1120-95-2]3-<strong>[1120-95-2]chloropyridazine</strong></strong> (211 mg, 1.84 mmol). The resulting suspension was stirred at 0 °C then warmed to RT overnight. The reaction mixture was diluted withethyl acetate (10 mL), washed with water, dried over sodium sulfate, and concentrated in vacuo to give cmde product. LC/MS: m/e 323.20 (M+H), 2.09 mm (LCMS Method 7).
 

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