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Chemical Structure| 78761-37-2 Chemical Structure| 78761-37-2

Structure of 78761-37-2

Chemical Structure| 78761-37-2

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Product Details of [ 78761-37-2 ]

CAS No. :78761-37-2
Formula : C20H19NO7
M.W : 385.37
SMILES Code : O=C(O)[C@H](OC(C1=CC=CC=C1)=O)[C@@H](OC(C2=CC=CC=C2)=O)C(N(C)C)=O
MDL No. :N/A

Safety of [ 78761-37-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 78761-37-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 78761-37-2 ]

[ 78761-37-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 313368-85-3 ]
  • [ 78761-37-2 ]
  • C14H19N3*C20H19NO7 [ No CAS ]
  • C14H19N3*C20H19NO7 [ No CAS ]
YieldReaction ConditionsOperation in experiment
In methanol; at 20 - 25℃; for 3h;Inert atmosphere; The separation of the formula (VI/A) L-DBMA salt from the formula (IV) racemic cis compound 2.29 g (10 mmol) cis racemate is dissolved in 12 ml methanol. A thin stream of a colourless solution of 2.70 g (7 mmol, 0.7 equiv.) (-)-dibenzoyl-L-tartaric acid mono(dimethylamide) (L-DBMA) made with 13 ml methanol is poured into the brownish solution stirred in an argon atmosphere in a 25 C water bath, the Erlenmeyer flask is rinsed with a further 2 ml methanol. After 2 minutes the yellow solution starts to become cloudy, and after another 1 minute a thick yellow suspension is obtained, which is then stirred for 3 hours in an argon atmosphere at room temperature. The precipitated product is filtered, then washed with methanol (5 + 2.5 ml) and diethyl ether (2 x 3 ml). The raw product dries to constant weight in 1 hour in air.The distomer raw product: 2.717 g light yellow powder, mp 210-213 C (decomposes) (yield: 88.5%, theoretical yield: 3.07 g, 5 mmol) chiral HPLC: 98.26% (VI/A) + 1.39% (VI) (+ 2 contaminants, total 0.35%)
 

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