Home Cart Sign in  
Chemical Structure| 78776-45-1 Chemical Structure| 78776-45-1

Structure of 78776-45-1

Chemical Structure| 78776-45-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 78776-45-1 ]

CAS No. :78776-45-1
Formula : C10H14O4
M.W : 198.22
SMILES Code : CC(O[C@H]1C=C[C@@H](OC(C)=O)CC1)=O

Safety of [ 78776-45-1 ]

Application In Synthesis of [ 78776-45-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 78776-45-1 ]

[ 78776-45-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 78776-45-1 ]
  • [ 50405-45-3 ]
  • 9,10-dimethyl-5,6-dihydro-2,6-methanopyrano[4,3-b]oxocin-7(2H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
73% With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In 1,4-dioxane; at 20 - 115℃; for 1.5h;Inert atmosphere; General procedure: To a stirred solution of cyclohex-2-ene-1,4-diyl diacetate 1 (71.4 mg, 360 mol) in 1,4-dioxane (3.0 mL) were added 4-hydroxy-6-methyl-2H-pyran-2-one 2a (37.8 mg, 300 mol), Pd2(dba)3*CHCl3 (15.5 mg, 15 mol), dppb (25.6 mg, 60 mol), and iPr2NEt (0.209 mL, 1.20 mmol) at rt, and stirring was continued for 30 min at the same temperature, under argon atmosphere. The reaction mixture was then allowed to heat to 115 C, and stirred for 1 h. After filtration of the reaction mixture using small amount of silica gel followed by concentration, the residue was chromatographed on silica gel with AcOEt-hexane (1:4 v/v) as eluent to give 9-methyl-5,6-dihydro-2,6-methanopyrano[4,3-b]oxocin-7(2H)-one 4a (43.8 mg, 214 mol, 72%) as colorless needles.
 

Historical Records

Technical Information

Categories