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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Inaccessible (Haz class 6.1), International USD 150+
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Chemical Structure| 78946-25-5 Chemical Structure| 78946-25-5

Structure of 78946-25-5

Chemical Structure| 78946-25-5

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Product Details of [ 78946-25-5 ]

CAS No. :78946-25-5
Formula : C9H8Br2O2
M.W : 307.97
SMILES Code : O=C(OC)C1=CC=C(CBr)C(Br)=C1
MDL No. :MFCD15527254
Boiling Point : No data available
InChI Key :CFJQBNFFHMBNKQ-UHFFFAOYSA-N
Pubchem ID :10804694

Safety of [ 78946-25-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314-H317
Precautionary Statements:P260-P280-P301+P312+P330-P301+P330+P331-P303+P361+P353-P305+P351+P338
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 78946-25-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 78946-25-5 ]

[ 78946-25-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 78946-25-5 ]
  • [ 115652-52-3 ]
  • methyl 3-bromo-4-(((1-(hydroxymethyl)cyclopropyl)amino)methyl)benzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
46% Into a 500-mL round-bottom flask, was placed <strong>[115652-52-3](1-aminocyclopropyl)methanol hydrochloride</strong> (6 g, 48.55 mmol, 2 equiv), K2CO3 (11 g, 79.59 mmol, 3.5 equiv) in MeCN (120 mL), The mixture was stirred at room temperature for 10 min. This was followed by the addition of a solution of methyl 3-bromo-4-(bromomethyl)benzoate (15 g, 48.71 mmol, 1 equiv) in MeCN (150 mL) dropwise with stirring at 0° C. over 2h. The resulting solution was stirred overnight at room temperature. The resulting mixture was concentrated under vacuum. The residue was purified by silica gel chromatography (EtOAc/pet. ether, 1:3) to afford the title compound as a yellow oil (7 g, 46percent yield). MS: (ES, m/z): 314,316 [M+H]+.
  • 2
  • [ 78946-25-5 ]
  • [ 90326-62-8 ]
 

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