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Chemical Structure| 79642-50-5 Chemical Structure| 79642-50-5
Chemical Structure| 79642-50-5

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DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Synonyms: Disuccinimidyl glutarate; DSG

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Product Details of DSG Crosslinker

CAS No. :79642-50-5
Formula : C13H14N2O8
M.W : 326.26
SMILES Code : O=C(ON1C(CCC1=O)=O)CCCC(ON2C(CCC2=O)=O)=O
Synonyms :
Disuccinimidyl glutarate; DSG
MDL No. :MFCD00153597
InChI Key :LNQHREYHFRFJAU-UHFFFAOYSA-N
Pubchem ID :4432628

Safety of DSG Crosslinker

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of DSG Crosslinker

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 79642-50-5 ]

[ 79642-50-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 745017-94-1 ]
  • [ 79642-50-5 ]
  • C48H74N6O13 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20℃; N- (N-hydroxysuccinimidylglutaryl) -MMAF (14) : disuccinimidyl glutarate (20flmol) and diisopropylethylamine (20flmol) were added to the solution of MMAF (1.4imol) in ACN (0.4m1) . The mixture was stirred at room temperature overnight.
 

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