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Chemical Structure| 850374-97-9 Chemical Structure| 850374-97-9

Structure of 850374-97-9

Chemical Structure| 850374-97-9

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Product Details of [ 850374-97-9 ]

CAS No. :850374-97-9
Formula : C15H22N2O3S
M.W : 310.41
SMILES Code : CC1=C(C=O)SC(C2CCN(C(OC(C)(C)C)=O)CC2)=N1
MDL No. :MFCD07368515

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Application In Synthesis of [ 850374-97-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 850374-97-9 ]

[ 850374-97-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3325-11-9 ]
  • [ 850374-97-9 ]
  • [ 1141395-60-9 ]
YieldReaction ConditionsOperation in experiment
EXAMPLE 2 Preparation of 3,5-dichlorobenzyl 4-{5-[(1H-benzotriazol-5-ylamino)methyl]-4-methylthiazol-2-yl}piperidine-1-carboxylate (13) The reduced analogue compounds can be synthesised as follows <strong>[3325-11-9]5-Aminobenzotriazole</strong> 1 (162 mg, 1.12 mmol) and commercially available tert-butyl 4-(5-formyl-4-methyl-1,3-thiazol-2-yl)piperidine-1-carboxylate 11 (250 mg, 0.81 mmol) is initially introduced in DCM/THF (2:1, 6 ml), acetic acid (46 mul, 0.81 mmol) is added, and the mixture is stirred at RT for 3 h. Sodium triacetoxyborohydride (0.31 g, 1.45 mmol) is subsequently added, and stirring is continued overnight. Saturated NaHCO3 solution is added to the batch, which is extracted 2* with ethyl acetate, dried over Na2SO4, filtered and evaporated to dryness. The colourless solid obtained is reacted further without further purification.
 

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