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Chemical Structure| 85514-85-8 Chemical Structure| 85514-85-8

Structure of 85514-85-8

Chemical Structure| 85514-85-8

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Product Details of [ 85514-85-8 ]

CAS No. :85514-85-8
Formula : C12H26O2
M.W : 202.33
SMILES Code : CCCCCCCCCC[C@H](O)CO
MDL No. :MFCD00798314

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Application In Synthesis of [ 85514-85-8 ]

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  • Downstream synthetic route of [ 85514-85-8 ]

[ 85514-85-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 51792-34-8 ]
  • [ 85514-85-8 ]
  • [ 126213-55-6 ]
YieldReaction ConditionsOperation in experiment
With p-toluenesulfonic acid monohydrate; In hexane; dichloromethane; toluene; INVENTION EXAMPLE 1 Synthesis of chiral 2-n-decyl-2,3-dihydro-thieno[3,4-b] [1,4]dioxine A solution of <strong>[51792-34-8]3,4-dimethoxythiophene</strong> (1.90 g), toluene (30 ml), (S)-1,2-dodecanediol (2.50 g) and p-toluenesulfonic acid monohydrate (100 mg) was heated at 95° C., continuously leading a N2-stream over the solution. After 24 h the reaction mixture was poured into ethyl acetate, washed with NaHCO3 and the organic phase was concentrated. Subsequent filtration over SiO2 using n-hexane/CH2Cl2 (98/2) as eluant resulted in pure product (2.40 g). 1H-NMR (CDCl3): delta6.29 (s, 2H), 4.15 (dd, 1H), 4.11 (m, 1H), 3.93 (dd, 1H), 1.67-1.20 (18H), 0.88 (t, 3H) ppm; specific rotation [alpha] =-88° at 25° C. and 436 nm in hexane (c=0.066).
 

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