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Chemical Structure| 860625-19-0 Chemical Structure| 860625-19-0

Structure of 860625-19-0

Chemical Structure| 860625-19-0

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Product Details of [ 860625-19-0 ]

CAS No. :860625-19-0
Formula : C14H16BrN3O
M.W : 322.20
SMILES Code : O=C(C1=CC(Br)=CC2=C1NC=C2C3CCNCC3)N

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Application In Synthesis of [ 860625-19-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 860625-19-0 ]

[ 860625-19-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 860625-19-0 ]
  • [ 6608-47-5 ]
  • 5-bromo-3-[1-(ethenylsulfonyl)-4-piperidinyl]-1H-indole-7-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With triethylamine; In dichloromethane; at 20℃; for 0.5h; To a solution of 5-bromo-3-(4-piperidinyl)-1 H-indole-7-carboxamide (500 mg, 1.3 mmol) in methylene chloride at room temperature, triethylamine (0.44 mL, 3.2 mmol) and 2- chloroethylsulfonyl chloride (0.168 mL, 1 .6 mmol) were added. The reaction mixture was stirred for 30 min. Removed the solvent, the residue was purified by combiflash to give the title compound (150 mg, 75%). LCMS m/z 413.8 (M+H), 1.96 min
  • 2
  • [ 1065181-58-9 ]
  • [ 860625-19-0 ]
 

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