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Chemical Structure| 87600-97-3 Chemical Structure| 87600-97-3

Structure of 87600-97-3

Chemical Structure| 87600-97-3

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Product Details of [ 87600-97-3 ]

CAS No. :87600-97-3
Formula : C5HCl3N2O
M.W : 211.43
SMILES Code : O=C(Cl)C1=C(Cl)N=CN=C1Cl
MDL No. :MFCD10698804

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Application In Synthesis of [ 87600-97-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 87600-97-3 ]

[ 87600-97-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 2339-58-4 ]
  • [ 87600-97-3 ]
  • [ 1605329-32-5 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In dichloromethane; for 0.5h; 4,6-Dichloropyrimidine-5-carbonyl chloride (590 mg, 2.79 mmol, prepared according to E.V.Tarasov et al. Synlett 2000, 5, 625-626) was dissolved in dichloromethane (3 ml) and TEA (389 muIota, 2.79 mmol) was added. To this solution, <strong>[2339-58-4]3-fluoro-5-methoxyaniline</strong> (394 mg, 2.79 mmol) dissolved in 3 ml dichloromethane was added dropwise and the mixture was stirred for 30 min. The reaction mixture was then diluted with dichloromethane, washed with 4% sodium bicarbonate solution, dried over magnesium sulphate, filtered and evaporated. The crude (800 mg, 56% purity, 51 % yield) was used in the next synthetic step without further purification. LRMS (m/z): 317 (M+1 )+
  • 2
  • [ 2339-58-4 ]
  • [ 87600-97-3 ]
  • [ 1605329-33-6 ]
 

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