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Chemical Structure| 879088-41-2 Chemical Structure| 879088-41-2

Structure of 879088-41-2

Chemical Structure| 879088-41-2

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Product Details of [ 879088-41-2 ]

CAS No. :879088-41-2
Formula : C11H9ClN2
M.W : 204.66
SMILES Code : NC1=CC=C(Cl)C(C2=NC=CC=C2)=C1
MDL No. :MFCD12024455
InChI Key :QWVLHTCIAZPQAY-UHFFFAOYSA-N
Pubchem ID :40151925

Safety of [ 879088-41-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H320-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 879088-41-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 879088-41-2 ]

[ 879088-41-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 879088-41-2 ]
  • [ 431888-57-2 ]
  • methyl 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoate [ No CAS ]
  • 2
  • [ 879088-41-2 ]
  • [ 32315-10-9 ]
  • [ 1197159-91-3 ]
  • 1-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)urea [ No CAS ]
YieldReaction ConditionsOperation in experiment
28% General procedure: The mixture of compound 5a (1 mmol) and DIEA (1 mmol) in anhydrous CH2Cl2 (5 mL) was added dropwise to the bis(trichloromethyl) carbonate (0.5 mmol) in anhydrous CH2Cl2 (5 mL) at -78 C. After 1 h, the temperature was allowed to warm up to room temperature. The mixture of compound 7a (1 mmol) and DIEA (1 mmol) in anhydrous CH2Cl2 (5 mL) was added in one portion. The mixture was stirred at room temperature for another 2 h and then quenched with saturated Na2CO3. Extract the aqueous solution with CH2Cl2 for three times. The organic layer was concentrated to give the residue, which was purified using flash chromatography (petroleum ether/THF, 1:1) to yield a white solid, yield 30%.
 

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[ 879088-41-2 ]

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[ 879088-41-2 ]

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