Structure of 88-24-4
*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
4.5
*For Research Use Only !
Change View
Size | Price | VIP Price | US Stock |
Global Stock |
In Stock | ||
{[ item.pr_size ]} |
Inquiry
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.discount_usd) ]} {[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} |
Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]} | Inquiry {[ item.pr_usastock ]} In Stock Inquiry - | {[ item.pr_chinastock ]} {[ item.pr_remark ]} In Stock 1-2 weeks - Inquiry - | Login | - + | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
1-2weeks
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price, item.pr_usd) ]}
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
In Stock
- +
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 88-24-4 |
Formula : | C25H36O2 |
M.W : | 368.55 |
SMILES Code : | OC1=C(C(C)(C)C)C=C(CC)C=C1CC2=CC(CC)=CC(C(C)(C)C)=C2O |
MDL No. : | MFCD00026296 |
InChI Key : | GPNYZBKIGXGYNU-UHFFFAOYSA-N |
Pubchem ID : | 6928 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
98.9% | EXAMPLE 13 Into the reactor described in Example 1 hereinbefore there are charged 58.5 g (0.25 g-mol) of 2,6-ditert.butyl4-ethylphenol, 1 g of a concentrated sulfuric acid and 19 g (0.25 g-mol) of methylal are added into the reactor at the temperature of 130 C. over 30 minutes. The reaction mass is treated and 26.2 g of 2,2'-methylene-bis-(4-ethyl-6-tert.butylphenol) are thus obtained which corresponds to 98.9% of the theoretical yield calculated for the reacted 2,6-ditert.butyl-4-ethylphenol (conversion of the latter is 57.5). | |
81% | Subsequent treatment of the obtained reaction mixture and separation of the desired product are performed following the procedure described in Example 2. 2,2'-methylenebis(4-ethyl-6-tert.butylphenol) is produced, m.p. 123-125 C, in 81% yield of theory. | |
Examples of the alkylidenebisphenols of group f) are 2,2'-methylenebis(6-tert-butyl-4-methylphenol), 2,2'-methylenebis-(6-tert-butyl-4-ethylphenol), 2,2'-methylenebis[4-methyl-6-(alpha-methylcyclohexyl)phenol], 2,2'-methylenebis(4-methyl-6-cyclohexylphenol), 2,2'-methylenebis(6-nonyl-4-methylphenol), 2,2'-methylenebis(4,6-di-tert-butylphenol), 2,2-ethylidenebis(4,6-di-tert-butylphenol), 2,2'-ethylidenebis(6-tert-butyl-4-isobutylphenol), 2,2'-methylenebis[6-(alpha-methylbenzyl)-4-nonylphenol], ... |
Therefore, examples of the bisphenol compound represented by the formula (IV) which is obtained by the condensation reaction are as follows. ... 2,2'-methylenebis(4,6-di-t-butylphenol), 2,2'-propylidenebis(6-t-butyl-4-methylphenol), 2,2'-ethylidenebis(6-t-butyl-4-methylphenol), 2,2'-methylenebis(6-t-butyl-4-nethylphenol), 2,2'-methylenebis(6-t-butyl-4-ethylphenol), 2,2'-ethylidenebis(6-t-butyl-4-propylphenol), | ||
Alkylated Monophenols ... 2,2'-Thio-bis-(6-tert-butyl-4-methylphenol), 4,4'-thio-bis-(6-tert-butyl-3-methylphenol), 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-(4-methyl-6-(alpha-methyl-cyclohexyl)-phenol, 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), ... | ||
Alkylated Monophenols ... o-tert-butylphenol. 2,6-Di-tert-butyl-4-methoxyphenol, 2,5-di-tert-butyl-hydroquinone, 2,5-di-tert-amyl-hydroquinone, 2,6-diphenyl-4-octa-decyloxyphenol. 4,4'-thio-bis-(6-tert-butyl-3-methylphenol), 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-(4-methyl-6-(alpha-methyl-cyclohexyl)-phenol), 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), 2,2'-methylene-bis-(4,6-di-tert-butylphenol), 2,2'-ethylidene-bis-(4,6-di-tert-butylphenol), ... | ||
Alkylated Monophenols ... 2,5-di-tert-butyl-hydroquinone, 2,5-di-tert-amyl-hydroquinone, 2,6-diphenyl-4-octa-decyloxyphenol. 4,4'-thio-bis-(6-tert-butyl-3-methylphenol), 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-(4-methyl-6-(alpha-methyl-cyclohexyl)-phenol), 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), 2,2'-methylene-bis-(4,6-di-tert-butylphenol), 2,2'-ethylidene-bis-(4,6-di-tert-butylphenol), ... | ||
Alkylated Monophenols ... 2,2'-Thio-bis-(6-tert-butyl-4-methylphenol), 4,4'-thio-bis-(6-tert-butyl-3-methylphenol), 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2 '-methylene-bis-(4-methyl-6-(alpha-methyl-cyclohexyl)-phenol), 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), ... | ||
Alkylated Monophenols ... 2,2'-thio-bis-(4-octylphenol), 4,4'-thio-bis-(6-tert-butyl-3-methylphenol) and 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-[4-methyl-6-(alpha-methylcyclohexyl)-phenol], 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), ... | ||
Alkylated Monophenols ... 2,2'-Thio-bis-(4-octylphenol) 4,4'-Thio-bis-(6-tert.butyl-3-methylphenol) 4,4'-Thio-bis-(6-tert.butyl-2-methylphenol) 2,2'-Methylene-bis-(6-tert.butyl-4-methylphenol) 2,2'-Methylene-bis-(6-tert.butyl-4-ethylphenol) 2,2'-Methylene-bis-(4-methyl-6-(alpha-methylcyclohexyl)-phenol) 2,2'-Methylene-bis-(4-methyl-6-cyclohexylphenol 2,2'-Methylene-bis-(6-nonyl-4-methylphenol) ... | ||
Alkylated Monophenols ... 2,2'-thio-bis-(4-octylphenol) 4,4'-thio-bis-(6-tert.-butyl-3-methylphenol) 4,4'-thio-bis-(6-tert.-butyl-2-methylphenol) 2,2'-Methylene-bis-(6-tert.-butyl-4-methylphenol) 2,2'-methylene-bis-(6-tert.-butyl-4-ethylphenol) 2,2'-methylene-bis-(4-methyl-6-(alpha-methylcyclohexyl)-phenol) 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol) 2,2'-methylene-bis-(6-nonyl-4-methylphenol) ... | ||
Alkylated monophenols ... 2,2'-thio-bis-(4-octyl-phenol), 4,4'-thio-bis-(6-tert-butyl-3-methylphenol) and 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-[4-methyl-6-(alpha-methylcyclohexyl)-phenol], 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), ... | ||
Specific examples of such electron accepting compounds are as follows: ... 4,4'-isopropylidene bis(2-tert-butylphenol), 4,4'-cyclohexylidene diphenol, 4,4'-isopropylidene bis(2-chlorophenol), 2,2'-methylene bis(4-methyl-6-tert-butylphenol), 2,2'-methylene bis(4-ethyl-6-tert-butylphenol), 4,4'-butylidene bis(6-tert-butyl-2-methylphenol), 1,1,3-tris(2-methyl-4-hydroxy-5-tert-butyl-phenyl)butane, 1,1,3-tris(2-methyl-4-hydroxy-5-cyclohexylphenyl)butane, ... | ||
Alkylated Monophenols ... 2,2'-Thio-bis-(6-tert-butyl-4-methylphenol), 4,4'-thio-bis-(6-tert-butyl-3-methylphenol), 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-(4-methyl-6-(alpha-methyl-cyclohexyl)-phenol), 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), ... | ||
Alkylated Monophenols ... 2,2'-Thio-bis-(4-octylphenol) 4,4'-Thio-bis-(6-tert.-butyl-3-methylphenol) 4,4'-Thio-bis-(6-tert.-butyl-2-methylphenol) 2,2'-Methylene-bis-(6-tert.-butyl-4-methylphenol) 2,2'-Methylene-bis-(6-tert.-butyl-4-ethylphenol) 2,2'-Methylene-bis-[4-methyl-6-(alphamethylcyclohexyl)-phenol] 2,2'-Methylene-bis-(4-methyl-6-cyclohexylphenol) 2,2'-Methylene-bis-(6-nonyl-4-methylphenol) ... | ||
Alkylated monophenols ... 2,2'-thio-bis(4-octylphenol) 4,4'-thio-bis(6-tert-butyl-3-methylphenol) 4,4'-thio-bis(6-tert-butyl-2-methylphenol) 2,2'-methylene-bis(6-tert-butyl-4-methylphenol) 2,2'-methylene-bis(6-tert-butyl-4-ethylphenol) 2,2'-methylene-bis[4-methyl-6-(alpha-methylcyclohexyl)phenol] 2,2'-methylene-bis(4-methyl-6-cyclohexylphenol) 2,2'-methylene-bis(6-nonyl-4-methylphenol) ... | ||
Alkylated monophenols ... 2,2'-thio-bis-(4-octylphenol), 4,4'-thio-bis-(6-tert-butyl-3-methylphenol), 4,4'-thio-bis-(6-tert-butyl-2-methylphenol). 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol), 2,2'-methylene-bis-(6-tert-butyl-4-ethylphenol), 2,2'-methylene-bis-[4-methyl-6-(alpha-methylcyclohexyl)-phenol], 2,2'-methylene-bis-(4-methyl-6-cyclohexylphenol), 2,2'-methylene-bis-(6-nonyl-4-methylphenol), ... | ||
Illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)-4-methylphenol 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) 2,2'-methylene-bis(3-t-butyl-5-methylphenol) | ||
Illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis-(2-t-butyl-5-methylphenol) 2,2'-methylene-bis 6-(2-t-methylcyclohexyl)-4-methylphenol 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) 2,2'-methylene-bis(3-t-butyl-5-methylphenol) | ||
illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis-6-(2-t-methylcyclohexyl)-4-methylphenol 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) | ||
illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)-4-methylphenol] 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) | ||
Alkylated monophenols ... 2,2'-Thio-bis-(4-octylphenol) 4,4'-Thio-bis-(6-tert-butyl-3-methyphenol) 4,4'-Thio-bis-(6-tert-butyl-2-methyphenol) 2,2'-Methylene-bis-(6-tert-butyl-4-methylphenol) 2,2'-Methylene-bis-(6-tert-butyl-4-ethylphenol) 2,2'-Methylene-bis-[4-methyl-6-(alpha-methylcyclohexyl)-phenol] 2,2'-Methylene-bis-(4-methyl-6-cyclohexylphenol) 2,2'-Methylene-bis-(6-nonyl-4-methylphenol) ... | ||
Illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)-4-methylphenol] 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) | ||
Illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)-4-methylphenol 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) | ||
illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)]-4-methylphenol 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) 2,2'-methylene-bis(3-t-butyl-5-methylphenol) | ||
Illustrative examples of the compound shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) and 2,2'-methylene-bis(3-t-butyl-5-methylphenol). | ||
illustrative examples of the compounds shown are: 2,2'-methylene-bis-(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)]-4-methylphenol 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) | ||
Alkylated Monophenols ... 4,4--thio-bis-(6-tert.-butyl-2-methylphenol) 2,2--Methylene-bis-(6-tert.butyl-4-methylphenol) 2,2--methylene-bis-(6-tert.-butyl-4-ethylphenol) 2,2--methylene-bis-(4-methyl-6-(alpha-methylcyclohexyl)-phenol ... | ||
Specific examples of the color developer for use in the present invention are as follows: ... 4,4'-isopropylidenebis(2-chlorophenol), 2,2'-methylenebis(4-methyl-6-tert-butylphenol), 2,2'-methylenebis(4-ethyl-6-tert-butylphenol), 4,4'-sec-butylidenebis(6-tert-butyl-2-cresol), ... | ||
Preferably exemplified are 1,1,3-tris(2-methyl-4-hydroxy-5-t-butylphenyl)butane, 1,1,3-tris(2-methyl-4-hydroxy-5-t-cyclohexylphenyl)butane, 4,4'-butylidenebis(6-t-butyl-3-methylphenol), 2,2'-methylenebis(4-ethyl-6-t-butylphenol), 1,3,5-tris(2,6-dimethyl-4-t-butyl-3-hydroxybenzyl) isocyanurate, 2-methyl-2-[[4-[[4-(phenylmethoxy)phenyl]sulfonyl]phenoxy]methyl]-oxirane, 4,4'-sulfonylbis(2,6-dibromophenol) and 2-(2'-hydroxy-5'-methylphenyl)benzotriazole. | ||
Also mentioned as exemplary are the hindered phenols in accord with the above formula wherein R4, R5 and R6 are all present.These include: ...4,4'-methylenebis(2,6-di-t-butylphenol)1,3,5-trimethyl-2,4,6-tris(3,5-di-t-butyl-4-hydroxybenzyl)benzene2,6-di-t-butyl-alpha-dimethylamino-p-cresol2,6-di-t-butyl-4-secbutylphenol2,2'-methylenebis(4-ethyl-6-t-butylphenol)2,2'-methylenebis(4-methyl-6-t-butylphenol)2,2'-methylenebis(6-(1-methylcyclohexyl)-p-cresol; and2,2'-methylenebis(4-methyl-6-cyclohexylphenol) | ||
Illustrative examples of the compounds shown are: 2,2'-methylene-bis(6-t-butyl-4-methylphenol) 2,2'-methylene-bis(6-t-butyl-4-ethylphenol) 4,4'-butylidene-bis(2,6-di-t-butylphenol) 4,4'-(2-butylidene)-bis(2-t-butyl-5-methylphenol) 2,2'-methylene-bis[6-(2-t-methylcyclohexyl)-4-methylphenol] 2,2'-methylene-bis(3-t-butyl-5-ethylphenol) 4,4'-methylene-bis(3,5-di-t-butylphenol) 4,4'-methylene-bis(3-t-butyl-5-methylphenol) |