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Chemical Structure| 885954-14-3 Chemical Structure| 885954-14-3

Structure of 885954-14-3

Chemical Structure| 885954-14-3

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Product Details of [ 885954-14-3 ]

CAS No. :885954-14-3
Formula : C13H14N2O4
M.W : 262.26
SMILES Code : O=C(C1=CC2=C(N(C(OC(C)(C)C)=O)N=C2)C=C1)O
MDL No. :MFCD04038509

Safety of [ 885954-14-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 885954-14-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 885954-14-3 ]

[ 885954-14-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1520-70-3 ]
  • [ 885954-14-3 ]
  • [ 1387634-77-6 ]
YieldReaction ConditionsOperation in experiment
94% With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20℃; for 16h; Preparation 25: terf-butyl 5-r(ethylsulfonyl)carbamovn-1 H-indazole-1 -carboxylate; A mixture of 1-(ferf-butoxycarbonyl)-1 H-indazole-5-carboxylic acid [preparation 24] (7g, 0.027mol), ethanesulphonamide (7g, 0.064mol), WSCDI (6.1 g, 0.032mol) and DMAP (8.2g, 0.067mol) in DCM (150ml) was stirred at room temperature for 16 hours. The reaction mixture was diluted with DCM (100ml), washed with aqueous HCI (3x100ml, 1 M), dried over Na2S04, filtered and evaporated to give the title compound as a white foamy solid (9g, 94percent).1H NMR (400 MHz, CDCI3) delta ppm 1 .48 (t, 3H) 1.75 (s, 9H) 3.66 (q, 2H) 7.99 (d, 1 H) 8.28-8.33 (d, 2H) 8.28-8.33 (s, 1 H) 8.52 (s, 1 H)
 

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