886500-59-0|2-Methoxy-4-(trifluoromethyl)benzyl bromide| Ambeed

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Quality Control of [ 886500-59-0 ] Purity: 98% SDS Specification

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Product Details of [ 886500-59-0 ]

CAS No. :	886500-59-0
Formula :	C₉H₈BrF₃O
M.W :	269.06
SMILES Code :	FC(C1=CC=C(C(OC)=C1)CBr)(F)F
MDL No. :	MFCD04115980
InChI Key :	WWAGWLZAZFSJRH-UHFFFAOYSA-N
Pubchem ID :	3688569

Safety of [ 886500-59-0 ]

GHS Pictogram:
Signal Word:	Danger
Hazard Statements:	H302-H315-H314
Precautionary Statements:	P260-P264-P270-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P332+P313-P362-P405-P501
Class:	8
UN#:	3261
Packing Group:	Ⅱ

Application In Synthesis of [ 886500-59-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 886500-59-0 ]

[ 886500-59-0 ] Synthesis Path-Downstream 1~1

1
[ 886500-59-0 ]
[ 436-77-1 ]
C₅₆H₅₈F₆N₂O₈⁽²⁺⁾*2Br^(1-) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
10.55 g	In dimethyl sulfoxide; at -20℃; for 12h;	Weigh 6.10g of <strong>[436-77-1]fangchinoline</strong>base, 8.50g of 2-methoxy-4-trifluoromethylbenzyl bromide dissolved in DMSO 150mLIn a 500 mL three-necked flask, 0.50 g of gamma-Al2O3-Na was added, and the temperature was lowered to -20 C, and the reaction was stirred for 12 h with stirring.All the <strong>[436-77-1]fangchinoline</strong> base was reacted, and after adding 200 mL of acetone, 2 g of activated carbon was added, and the solid was removed by filtration, and the filtrate was steamed to a volume of 50 mL.After crystallization overnight at room temperature, TLC traces the reaction and separation and purification of the product, and the solid is dried at 60 C for 4 h.The product was 10.55 g as a pale yellow powder. M.p.(1334.9862), molecular formula: C64H63O9N2F9Br2, that is, compound III100 in Table 2.

References: [1]Patent: CN109678872,2019,A .Location in patent: Paragraph 0140-0141.

Historical Records

Technical Information

• Alkyl Halide Occurrence • General Reactivity • Grignard Reaction • Hiyama Cross-Coupling Reaction • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Nomenclature of Ethers • Preparation of Ethers • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Dihalides • Reactions of Ethers • Stille Coupling • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling

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[ 886500-59-0 ]

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CAS No.: 886500-59-0

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