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Chemical Structure| 89-78-1 Chemical Structure| 89-78-1
Chemical Structure| 89-78-1

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DL-Menthol is a calming menthol that can activate GABAA receptors, commonly used to improve sleep and alleviate anxiety.

Synonyms: Racementhol; (±)-Menthol; CCRIS 375

4.5 *For Research Use Only !

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Product Details of DL-Menthol

CAS No. :89-78-1
Formula : C10H20O
M.W : 156.27
SMILES Code : O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1
Synonyms :
Racementhol; (±)-Menthol; CCRIS 375
MDL No. :MFCD00062983

Safety of DL-Menthol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335-H413
Precautionary Statements:P273-P301+P312+P330-P302+P352-P305+P351+P338

Application In Synthesis of DL-Menthol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 89-78-1 ]

[ 89-78-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 89-78-1 ]
  • [ 98-55-5 ]
  • [ 498-81-7 ]
  • 2
  • [ 221044-05-9 ]
  • [ 201230-82-2 ]
  • [ 89-78-1 ]
  • 2-isopropyl-5-methylcyclohexyl 1-(pyrimidin-2-yl)-1H-indole-2-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% With rhodium(III) chloride trihydrate; copper diacetate; In N,N-dimethyl-formamide; at 90℃; under 760.051 Torr; for 10h;Sealed tube; AddN-pyrimidinylpurine 1a (0.2 mmol), RhCl3•3H2O (0.004 mmol), Cu(OAc)2(0.4 mmol) and2-isopropyl-5-methylcyclohexanol 2r (1.0 mmol) to 2.0 mL DMF, in a Young tube setafter the change of carbon monoxide three times, charged with carbon monoxide (1 atm), the reaction and after 90 deg.] C oil bath for 10 hours, the reaction was stopped, to be antisolution was cooled to room temperature, ethyl acetate and saturated The saline is washed and extracted several times.The organic phase was dried over anhydrous sodium sulfateand filtered.The solvent was evaporated to dryness, and ethyl acetate / petroleum ether (1:10to 1:1).The product was a white solid with a yield of 61%.
 

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