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Chemical Structure| 89479-61-8 Chemical Structure| 89479-61-8

Structure of 89479-61-8

Chemical Structure| 89479-61-8

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Product Details of [ 89479-61-8 ]

CAS No. :89479-61-8
Formula : C9H17NO2
M.W : 171.24
SMILES Code : O=C(OCC)CNC1CCCC1
MDL No. :MFCD11150381

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Application In Synthesis of [ 89479-61-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 89479-61-8 ]

[ 89479-61-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 89479-61-8 ]
  • [ 1211443-58-1 ]
  • 2
  • [ 3177-20-6 ]
  • [ 89479-61-8 ]
  • methyl 2-chloro-4-(cyclopentyl(2-ethoxy-2-oxoethyl)amino)pyrimidine-5-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% With sodium carbonate; In N,N-dimethyl-formamide; at 20℃; <strong>[3177-20-6]methyl 2,4,-dichloropyrimidine-5-carboxylate</strong> (20.70 g, 100 mmol), N,N-dimethylformamide (104 mL) was added to a three-necked flask, stirred and dissolved, and sodium carbonate (26.50 g, 250 mmol) was added. stir evenly and add ethyl 2-cyclopentylaminoacetate (17.12 g, 100 mmol) was reacted at room temperature for 6-8 hours. At the end of the reaction, water (207 mL) was added, and the mixture was separated, and the aqueous phase was extracted twice with dichloromethane (104 mL), and the organic phase brine (104 mL) was washed once, dried over anhydrous sodium sulfate, filtered, concentrated, The mixture is pulverized with isopropanol and petroleum ether. The solid is separated by filtration and dried in vacuo to give methyl 2-chloro-4-(cyclopentyl(2-ethoxy-2-oxoethyl)amino)pyrimidine-5-carboxylate (30.76g, 90percent).
 

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