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[ CAS No. 89943-13-5 ]

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2D
Chemical Structure| 89943-13-5
Chemical Structure| 89943-13-5
Structure of 89943-13-5 *Storage: {[proInfo.prStorage]}

Quality Control of [ 89943-13-5 ]

Purity: {[proInfo.showProBatch.pb_purity]}

Related Doc. of [ 89943-13-5 ]

SDS

Product Details of [ 89943-13-5 ]

CAS No. :89943-13-5MDL No. :MFCD16877218
Formula :C7H10N2OBoiling Point :-
Linear Structure Formula :-InChI Key :-
M.W :138.17Pubchem ID :21387881
Synonyms :

Computed Properties of [ 89943-13-5 ]

TPSA : 48.1 H-Bond Acceptor Count : 3
XLogP3 : 0.5 H-Bond Donor Count : 1
SP3 : 0.29 Rotatable Bond Count : 2

Safety of [ 89943-13-5 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 89943-13-5 ]

  • Downstream synthetic route of [ 89943-13-5 ]

[ 89943-13-5 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 89943-13-5 ]
  • [ 211105-11-2 ]
  • ethyl 2-(4-((3-ethoxypyridin-4-yl)carbamoyl)phenyl)-2-methylpropanoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% 4- (1-ethoxy-2-methyl-1-oxopropan-2-yl) benzoic acid (580 mg, 2.45 mmol)Thionyl chloride (880 mg, 7.36 mmol),Toluene (6 mL) was reacted at 80 C. for 1 hour.The reaction solution was concentrated, and the concentrated residue was dissolved in tetrahydrofuran(3 mL). 3-Ethoxypyridin-4-amine (340 mg, 2.45 mmol),Diisopropylethylamine (640 mg,6.3 mmol), and the mixture was reacted at room temperature for 2 hours.Water was added and the mixture was extracted with ethyl acetate.The organic layer was washed with saturated brine, dried over anhydrous sodium sulfate. After removing anhydrous sodium sulfate by filtration,The solvent was distilled off under reduced pressure and the residue was purified by flash chromatography (eluent: n-heptane / ethyl acetate)To give the target product (660 mg, yield 75%).
Historical Records

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[ 89943-13-5 ]

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Pyridines

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