Home Cart Sign in  
Chemical Structure| 90610-24-5 Chemical Structure| 90610-24-5

Structure of 90610-24-5

Chemical Structure| 90610-24-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 90610-24-5 ]

CAS No. :90610-24-5
Formula : C9H12ClNO3
M.W : 217.65
SMILES Code : OC1=CC=C(CN)C=C1C(OC)=O.[H]Cl
MDL No. :MFCD09877748
Boiling Point : No data available

Safety of [ 90610-24-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 90610-24-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 90610-24-5 ]

[ 90610-24-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 219607-46-2 ]
  • [ 90610-24-5 ]
  • [ 1164275-22-2 ]
YieldReaction ConditionsOperation in experiment
91% Synthesis of DJTE3:2-Hydroxy-5-[(7-methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3-carbonyl)-amino]-methyl}-benzoic acid methyl ester 6; Acid 5 (0.4 g, 1.31 mmol, 1 eq), 5-aminomethyl salicylic acid methyl ester HCl (0.26 g, 1.43 mmol, 1.095 eq), 1-hydroxybenzotriazole (0.196 g, 1.44 mmol, 1.102 eq) and N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide.HCl (0.276 g, 2.176 mmol, 1.66 eq) were dissolved in DCM (2 ml) and were stirred at ambient temperature for 18 h. The reaction mixture was poured into water (10 ml)and DCM (10 ml) was added, the pH was adjusted to 7 with dil. aq. NaOH and the organic layer was poured off. The aqueous layer was then extracted with DCM (2×10 ml) and the combined organic layers were washed with water (2×10 ml), were washed with brine (10 ml), were dried over Na2SO4, filtered and the solvent was removed in vacuo. The product was purified via column chromatography eluted with a gradient from 1:1 to 1:3 CyH:EtOAc (Rf product=0.7, Rf acid 5=0.4 in DCM/5% MeOH, UV, CAM). This gave 0.558 g (91%) of the product as a white solid. 1H-NMR (CDCl3) 500 MHz: delta (ppm)=0.94 (3H, t, J=7.1 Hz, CH2CH2CH3), 1.35-1.50 (4H, m, CH2CH2CH3), 1.81 (2H, quin, J=7.8 Hz, CH2CH2CH2CH3), 3.93 (3H, s, COOCH3), 3.97 (3H, s, COCH3), 4.13 (2H, t, J=6.9 Hz, OCH2CH2), 4.58 (2H, d, J=5.9 Hz, NHCH2C), 6.93 (1H, d, J=8.9 Hz, CHCOCH3), 6.95 (1H, d, J=8.8 Hz, CHCOH), 7.45 (1H, d, J=8.5 Hz, CHCHCOCH3), 7.50 (1H, dd, J=2.3 Hz, J=8.5 Hz, CHCHCOH), 7.84 (1H, d, J=2.3 Hz, CHCCOH), 8.90 (1H, s, CCCHCCONH), 9.12 (1H, br.s, CNHCOC), 9.97 (1H, br.t, J=5.5 Hz, NHCH2C), 10.69 (1H, s, COH). 13C-NMR (CDCl3) 125 MHz: delta (ppm)=14.0 (CH3), 22.4 (CH2), 28.0 (CH2), 29.9 (CH2), 42.8 (NCH2), 52.2 (COOCH3), 56.3 (OCH3), 73.8 (OCH2), 109.1 (CH), 112.2 (C), 114.2 (C), 117.9 (CH), 119.4 (C), 125.3 (CH), 129.1 (CH), 129.6 (C), 132.4 (C), 133.5 (C), 135.5 (CH), 145.1 (CH), 154.4 (CH), 160.8 (C), 162.1 (CO), 163.6 (CO), 170.4 (CO). IR Spectrum; evaporated film: v(cm-1)=32.45, 29.53, 1672, 1621, 1534, 1495, 1355, 1288, 1213, 1110. MS-ES (negative): 467.7 (M-H+). MS-ES (positive): 469.8 (M+H+). HPLC: 14.615 min.
  • 2
  • [ 219607-46-2 ]
  • [ 90610-24-5 ]
  • [ 1164275-16-4 ]
 

Historical Records

Technical Information

Categories