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Chemical Structure| 90642-63-0 Chemical Structure| 90642-63-0

Structure of 90642-63-0

Chemical Structure| 90642-63-0

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Product Details of [ 90642-63-0 ]

CAS No. :90642-63-0
Formula : C9H14ClNO
M.W : 187.67
SMILES Code : CC(N)C1=CC=C(OC)C=C1.[H]Cl
MDL No. :MFCD12198855

Safety of [ 90642-63-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 90642-63-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 90642-63-0 ]

[ 90642-63-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 90642-63-0 ]
  • [ 56844-12-3 ]
  • (6-Bromothieno[2,3-d]pyrimidin-4-yl)-[1-(4-methoxyphenyl)ethyl]amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
41% With triethylamine; In N,N-dimethyl-formamide; at 25℃; for 20h; A mixture of <strong>[56844-12-3]6-bromo-4-chlorothieno[2,3-d]pyrimidine</strong> (prepared as disclosed in WO 2003053446) (500 mg, 2.0 mmol), the amine hydrochloride (compound 117) (563 mg, 3.0 mmol) and triethylamine (505 mg, 5.0 mmol) in DMF (7 mL) was stirred at approximately 25 C. for 20 hours. After cooling, the mixture was diluted with water (20 mL) and extracted with ether (3*25 mL). The combined organics were washed with water, saturated brine, and dried (Na2SO4). Filtration and removal of solvent gave product as an off-white solid, 300 mg, 0.83 mmol, 41 percent yield.
 

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