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Chemical Structure| 90815-00-2 Chemical Structure| 90815-00-2

Structure of 90815-00-2

Chemical Structure| 90815-00-2

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Product Details of [ 90815-00-2 ]

CAS No. :90815-00-2
Formula : C16H12ClNO
M.W : 269.73
SMILES Code : O=CC1=CN(CC2=CC=CC=C2Cl)C3=C1C=CC=C3
MDL No. :MFCD01590286

Safety of [ 90815-00-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H317
Precautionary Statements:P264-P270-P301+P312-P330-P302+P352-P333+P313-P321-P261-P272-P280-P363-P501

Application In Synthesis of [ 90815-00-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 90815-00-2 ]

[ 90815-00-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 90815-00-2 ]
  • [ 6882-68-4 ]
  • 14-[N-(2-chlorobenzyl)-1H-indo-3-ylmethylene]sophoridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
31% General procedure: A 100mL round-bottomed flask was charged with <strong>[6882-68-4]sophoridine</strong> (1.24g, 5mmol), NaH (2.4g, 100mmol) and anhydrous tetrahydrofuran (50mL). The solution was stirred at room temperature for 1h followed by addition of N-substituted indole-carboxyaldehyde (5mmol) and then refluxed for 48h. The reaction mixture was cooled and then poured into water slowly (100mL). It was then extracted with dichloromethane (3×40mL). The combined phases were dried with anhydrous Na2SO4 and concentrated to obtain crude product. The residue was purified by silica gel flash column chromatography (methanol/dichloromethane, 2%) to afford 5a-5y in 24%-53% yields.
 

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