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Chemical Structure| 92075-16-6 Chemical Structure| 92075-16-6

Structure of 92075-16-6

Chemical Structure| 92075-16-6

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Product Details of [ 92075-16-6 ]

CAS No. :92075-16-6
Formula : C7H14N2O
M.W : 142.20
SMILES Code : O=C1NCCN1C(C)(C)C
MDL No. :MFCD00832245

Safety of [ 92075-16-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 92075-16-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 92075-16-6 ]

[ 92075-16-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3107-19-5 ]
  • [ 92075-16-6 ]
  • 1-tert-butyl-3-(2,6-dichloro-4-nitrophenyl)imidazolidin-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
37% Example 69A 1-tert-Butyl-3-(2,6-dichloro-4-nitrophenyl)imidazolidin-2-one Under argon, a solution of 1.48 g (10.5 mmol) of 1-tert-butylimidazolidin-2-one in THF (10 ml) was cooled to 0 C., 1.60 g (14.3 mmol) of potassium tert-butoxide were added a little at a time and the mixture was stirred at RT for 30 min. A solution of 2.00 g (9.52 mmol) of <strong>[3107-19-5]1,3-dichloro-2-fluoro-5-nitrobenzene</strong> in THF (7 ml) was added and the mixture was stirred at 0 C. for 2 h. For work-up, the reaction mixture was diluted with water. The mixture was extracted three times with ethyl acetate and the organic phase was dried with magnesium sulfate, filtered on a rotary evaporator and concentrated. The residue was dissolved in ethyl acetate, absorbed on diatomaceous earth and purified by flash chromatography (cyclohexane/ethyl acetate 9:1?7:1). This gave 1.18 g (37% of theory) of the title compound. LC-MS (Method 3): Rt=1.11 min; m/z=332 (M+H)+.
 

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