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Chemical Structure| 922520-32-9 Chemical Structure| 922520-32-9

Structure of 922520-32-9

Chemical Structure| 922520-32-9

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Product Details of [ 922520-32-9 ]

CAS No. :922520-32-9
Formula : C10H13NO3
M.W : 195.22
SMILES Code : O=C(OC)C1=CC=C(OC)C(C)=C1N

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Application In Synthesis of [ 922520-32-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 922520-32-9 ]

[ 922520-32-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4434-13-3 ]
  • [ 922520-32-9 ]
  • [ 923274-98-0 ]
YieldReaction ConditionsOperation in experiment
65% Example 115 4-Methoxy-3-methyl-2-[(5-methyl-pyridine-2-carbonyl)-amino]-benzoic acid methyl ester (115) 2-Amino-4-methoxy-3-methyl-benzoic acid methyl ester (400 mg, 2 mmol) and 5-methyl-pyridine-2-carboxylic acid (280 mmol, 2 mmol) where dissolved in dichloro-methane (8 ml) and pyridine (1 ml). Phosphorous oxychloride (0.37 ml) was added while cooling on ice-bath. The mixture was left at 0 C. for 1 h then allowed to attain room temperature. Aqueous sodium hydroxide (20 ml, IM) was added and the mixture were extracted with dichloromethane. Purification by column chromatography on silica gel (ether-pentane 1:1) gave pure title compound (410 mg, 65%). MS (M-H)+ 315.1
 

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