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Chemical Structure| 931-20-4 Chemical Structure| 931-20-4

Structure of 931-20-4

Chemical Structure| 931-20-4

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Product Details of [ 931-20-4 ]

CAS No. :931-20-4
Formula : C6H11NO
M.W : 113.16
SMILES Code : O=C1N(C)CCCC1
MDL No. :MFCD00006555
InChI Key :GGYVTHJIUNGKFZ-UHFFFAOYSA-N
Pubchem ID :13603

Safety of [ 931-20-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 931-20-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 931-20-4 ]

[ 931-20-4 ] Synthesis Path-Downstream   1~6

  • 2
  • [ 10447-29-7 ]
  • [ 931-20-4 ]
  • 3-(quinoline-4-carbonyl)-1-methyl-piperidin-2-one [ No CAS ]
  • 3
  • [ 1721-26-2 ]
  • [ 931-20-4 ]
  • 3-[1-Hydroxy-1-(2-methyl-pyridin-3-yl)-meth-(Z)-ylidene]-1-methyl-piperidin-2-one [ No CAS ]
  • 4
  • [ 931-20-4 ]
  • [ 25077-25-2 ]
YieldReaction ConditionsOperation in experiment
56% With silver tetrafluoroborate; water; Selectfluor; In acetone; at 40℃; for 1h;Schlenk technique; Inert atmosphere; General procedure: To a 1-dram vial was added sequentially 1a (18.9 mg, 0.100 mmol), AgBF4 (77.9 mg, 0.400 mmol), Selectfluor (142 mg, 0.400 mmol) and 1 :9 acetone: H20 (0.5 mL) The resulting mixture was heated to 40 C and held at this temperature. After 1 h, the reaction mixture was partitioned with EtOAc (0.5 mL) and H20 (0.5 mL) and the phases were separated. The aqueous phase was extracted with EtOAc (1.5 mL c 3) and the combined organic layers were concentrated under reduced pressure. The crude residue was purified by preparative thin-layer chromatography (50% EtO Ac/hexanes) to provide A-(4-fl uorobutyl )- A'-form yl benzam i de (2a) (18.0 mg, 81%) as a pale yellow oil. NMR (600 MHz, CDCh): d 8.93 (s, 1H), 7.57 (t, J= 7.2 Hz, 1H), 7.53-7.48 (m, 4H), 4.48 (dt, J= 47.6, 5.6 Hz, 2H), 3.92 (t, J= 7.1 Hz, 2H), 1.82-1.72 (m, 4H); 13C NMR (151 MHz, CDCh): 172.5, 164.3, 133.7, 132.3, 129.1, 128.9, 83.6 (d, J = 165.2 Hz), 40.2, 28.0 (d, J= 20.2 Hz), 24.2 (d, J= 5.0 Hz); 19F NMR (376 MHz, CDCh): d -217.5 - -217.9 (m, 1F); HRMS (ESI): Calc?d for Ci2Hi4FN02Na [M+Na]+: 246.0906, found: 246.0906.
  • 6
  • [ 20845-34-5 ]
  • [ 931-20-4 ]
 

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