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Chemical Structure| 937668-63-8 Chemical Structure| 937668-63-8

Structure of 937668-63-8

Chemical Structure| 937668-63-8

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Product Details of [ 937668-63-8 ]

CAS No. :937668-63-8
Formula : C8H6BrN3O
M.W : 240.06
SMILES Code : OC1=C2C(Br)=CC=CC2=NC(N)=N1
MDL No. :MFCD18379108
InChI Key :WABUXSHYCDPHKN-UHFFFAOYSA-N
Pubchem ID :135704457

Safety of [ 937668-63-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 937668-63-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 937668-63-8 ]

[ 937668-63-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2597-44-6 ]
  • [ 937668-63-8 ]
  • [ 50919-07-8 ]
  • C18H19N5O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 1,3-bis-(diphenylphosphino)propane; potassium acetate; palladium diacetate; In tetrahydrofuran; at 100℃; under 37503.8 Torr; for 16h;Autoclave; Inert atmosphere; General procedure: Step 1. A 75-ml stainless steel autoclave was charged under N2 atmosphere with 7j (0.5 g, 2.08 mmol), benzylamine (1.14 mL, 10.4 mmol), Pd(OAc)2 (5 mg, 0.021 mmol), 1.3 bis(diphenylphosphino)propane (17.3 mg, 0.042 mmol), potassium acetate (408 mg, 4.17 mmol) in THF (15 mL). The autoclave was closed and pressurized to 50 bar CO and the reaction was carried out for 16 hours at a temperature of 100C. The solvent was removed by filtration and the residue was dissolved in DCM. The precipitate was filtered off, washed with DCM. The residue was dissolved in DMF and filtered to remove the catalyst and salt. The filtrate was concentrated under reduced pressure to obtain the crude desired intermediate D.
 

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