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Chemical Structure| 941696-22-6 Chemical Structure| 941696-22-6

Structure of 941696-22-6

Chemical Structure| 941696-22-6

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Product Details of [ 941696-22-6 ]

CAS No. :941696-22-6
Formula : C8H11BrN2
M.W : 215.09
SMILES Code : NC1=C(C)C=C(Br)C=C1NC

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Application In Synthesis of [ 941696-22-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 941696-22-6 ]

[ 941696-22-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 941696-22-6 ]
  • [ 54439-75-7 ]
  • [ 941696-23-7 ]
YieldReaction ConditionsOperation in experiment
With oxygen; pyrographite; In xylene; for 12h;Heating / reflux; Example 16 6-bromo-2-(2-chloro-4-methoxyphenyl)-1,4-dimethyl-1H-benzimidazole Activated carbon (Darco KB (trade name), manufactured by Aldrich Inc.); 100 mg) was added to the compound (200 mg) produced in Example 15 and <strong>[54439-75-7]2-<strong>[54439-75-7]chloro-4-methoxybenzaldehyde</strong></strong> (160 mg) in xylene solution (2 mL), followed by refluxing under heat for 12 hours under oxygen atmosphere. The reaction solution was cooled to room temperature, ethyl acetate was added thereto, and the reaction solution was subjected to filtration with Celite (trade name). The filtrate was concentrated under reduced pressure, whereby obtained solid was added with hexane, and filtrated to obtain a title compound (260 mg) having the following physical properties. TLC: Rf, 0.36 (toluene:ethyl acetate=3:1); 1H-NMP (300 MHz, CDCl3): delta 7.71 (m, 1H), 7.55 (d, J=8.7 Hz, 1H), 7.27 (d, J=2.4 Hz, 1H), 7.24 (m, 1H), 7.10 (dd, J=8.7, 2.4 Hz, 1H), 3.89 (s, 3H), 3.59 (s, 3H), 2.54 (s, 3H).
 

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