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Chemical Structure| 943995-31-1 Chemical Structure| 943995-31-1

Structure of 943995-31-1

Chemical Structure| 943995-31-1

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Product Details of [ 943995-31-1 ]

CAS No. :943995-31-1
Formula : C4H4ClN3O
M.W : 145.55
SMILES Code : OC1C(N)=NC(Cl)=NC=1
MDL No. :MFCD24627626

Safety of [ 943995-31-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 943995-31-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 943995-31-1 ]

[ 943995-31-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 943995-31-1 ]
  • [ 106-93-4 ]
  • [ 1303587-99-6 ]
YieldReaction ConditionsOperation in experiment
72% With potassium carbonate; In dichloromethane; for 4h;Reflux; 4-Amino-2-chloropyrimidin-5-ol (67; 3.75 g, 25.8 mmol) was taken up in CH2CI2 (2500 mL) along with 1,2-dibromoethane (4.85 g, 25.8 mmol) and 2C03 (10.68 g, 77.4 mmol). The resulting reaction mixture was refluxed for 4 h. The solid in the mixture was removed by filtration. The filtrate was concentrated, and the residue was purified by column chromatography to obtain 2-chloro-7,8-dihydro-6H-pyrimido[5,4-b][l ,4]oxazine (68; 3.18 g, 72% yield). MS (ESI) calcd for C6H6C1N30: 171.58; found 173 [M+H].
 

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