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Chemical Structure| 98837-46-8 Chemical Structure| 98837-46-8

Structure of 98837-46-8

Chemical Structure| 98837-46-8

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Product Details of [ 98837-46-8 ]

CAS No. :98837-46-8
Formula : C19H16NOP
M.W : 305.31
SMILES Code : P(/N=C/C1=CC=CC=C1)(=O)(C2=CC=CC=C2)C3=CC=CC=C3
MDL No. :N/A

Safety of [ 98837-46-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P264-P270-P301+P312-P330-P501

Application In Synthesis of [ 98837-46-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 98837-46-8 ]

[ 98837-46-8 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 4079-54-3 ]
  • [ 98837-46-8 ]
  • 2-hydroxy-1-(4-methylphenyl)-3-(N-diphenylphosphinoylamino)-3-phenylpropan-1-one [ No CAS ]
  • 2-hydroxy-1-(4-methylphenyl)-3-(N-diphenylphosphinoylamino)-3-phenylpropan-1-one [ No CAS ]
  • 2-hydroxy-1-(4-methylphenyl)-3-(N-diphenylphosphinoylamino)-3-phenylpropan-1-one [ No CAS ]
  • 2
  • [ 4079-54-3 ]
  • [ 98837-46-8 ]
  • 2-hydroxy-1-(4-methylphenyl)-3-(N-diphenylphosphinoylamino)-3-phenylpropan-1-one [ No CAS ]
  • 2-hydroxy-1-(4-methylphenyl)-3-(N-diphenylphosphinoylamino)-3-phenylpropan-1-one [ No CAS ]
  • 3
  • [ 5760-20-3 ]
  • [ 98837-46-8 ]
  • C29H26N3OP [ No CAS ]
  • N-((1R,2R)-2-amino-1-phenyl-2-(quinolin-2-yl)ethyl)-P,P-diphenylphosphinic amide [ No CAS ]
  • N-((1S,2R)-2-amino-2-(6-methylpyridin-2-yl)-1-phenylethyl)-P,P-diphenylphosphinic amide [ No CAS ]
YieldReaction ConditionsOperation in experiment
With C21H13BrO3; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0℃; for 66h; General procedure: a method for preparing a chiral 1,2-bis (hetero) aryl ethylenediamine compound, according to the following steps: 0.13 mmol of the imine of formula 4.1a, 0.01 mmol of the serial number in Embodiment 1 is 15 The catalyst was dissolved in 0.5mL of CH2Cl2, the reaction system was cooled to 0 , stirred for 10min, and then added 0.1mmol formula 4.2 aminoamine pyridine and 0.07mmol DBU, continue the reaction, TLC detection of the reaction process, to The pyridine completely disappeared (about t hours). After the reaction mixture was concentrated under reduced pressure, the target product was obtained by column chromatography, and the reaction process was as follows
  • 4
  • [ 5760-20-3 ]
  • [ 98837-46-8 ]
  • C29H26N3OP [ No CAS ]
  • N-((1R,2R)-2-amino-1-phenyl-2-(quinolin-2-yl)ethyl)-P,P-diphenylphosphinic amide [ No CAS ]
  • N-((1S,2R)-2-amino-2-(6-methylpyridin-2-yl)-1-phenylethyl)-P,P-diphenylphosphinic amide [ No CAS ]
YieldReaction ConditionsOperation in experiment
With (S)-4-bromo-2'-(4-(tert-butyl)phenyl)-3-hydroxy-[1,1'-binaphthalene]-2-carbaldehyde; 1,8-diazabicyclo[5.4.0]undec-7-ene; In o-xylene; at -10℃; for 46h; a method for preparing a chiral 1,2-bis (hetero) aryl ethylenediamine compound, according to the following steps: 0.13 mmol of the imine of formula 4.1b, 0.01 mmol of the serial number in Example 4 is 6 The catalyst was dissolved in 1mL of o-xylene, the reaction system was cooled to -10 , stirred for 10min, and then added 0.1mmol of 4.2 aminoamine pyridine and 0.07mmol of DBU, continue the reaction, TLC detection of the reaction process Aminopyridine disappeared completely (about t hours). After the reaction mixture was concentrated under reduced pressure, the target product was obtained by column chromatography, and the reaction process was as follows
 

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