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Chemical Structure| 99198-80-8 Chemical Structure| 99198-80-8

Structure of 99198-80-8

Chemical Structure| 99198-80-8

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Product Details of [ 99198-80-8 ]

CAS No. :99198-80-8
Formula : C16H23NO3
M.W : 277.36
SMILES Code : O=C(N1CCC(CCCO)CC1)OCC2=CC=CC=C2
MDL No. :MFCD04973406
InChI Key :LQEJJAZXQQCBBT-UHFFFAOYSA-N
Pubchem ID :14989193

Safety of [ 99198-80-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 99198-80-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 99198-80-8 ]

[ 99198-80-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7037-49-2 ]
  • [ 501-53-1 ]
  • [ 99198-80-8 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In dichloromethane; water; EXAMPLE 105 To a stirred mixture of methylene chloride (400 ml) and water (40 ml) are added dropwise benzyloxycarbonyl chloride (100 g) and a solution of 3-(4-piperidyl)propanol (84 g) and triethylamine (65 g) in methylene chloride (100 ml) for 45 minutes at room temperature. After addition is completed, stirring is continued for further 1 hour. The methylene chloride layer is separated, washed with water, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. Vacuum distillation of the oily residue is carried out to remove the low boiling material (50°-60° C./5 mmHg). 3-(1-Benzyloxycarbonyl-4-piperidyl)propanol (110 g) is obtained as a yellow oily residue. IR numaxneat cm-1: 3400(OH), 1680(C=O)
 

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