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Chemical Structure| 10433-52-0 Chemical Structure| 10433-52-0
Chemical Structure| 10433-52-0

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Synonyms: O-Benzyl-D-serine

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Product Details of H-D-Ser(Bzl)-OH

CAS No. :10433-52-0
Formula : C10H13NO3
M.W : 195.22
SMILES Code : [H][C@@](N)(COCC1=CC=CC=C1)C(O)=O
Synonyms :
O-Benzyl-D-serine
MDL No. :MFCD00065936
InChI Key :IDGQXGPQOGUGIX-SECBINFHSA-N
Pubchem ID :112114

Safety of H-D-Ser(Bzl)-OH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of H-D-Ser(Bzl)-OH

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10433-52-0 ]

[ 10433-52-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1233494-98-8 ]
  • [ 10433-52-0 ]
  • 2
  • [ 24424-99-5 ]
  • [ 10433-52-0 ]
  • [ 79069-15-1 ]
YieldReaction ConditionsOperation in experiment
3 and 4: (Scheme 1): The corresponding O-benzyl protected D- or L-serine 1 or 2 (5.00 g, 25.6 mmol) was added slowly to a suspension of Li-AlH4 (1.46 g, 38.5 mmol) in THF (100 ml). The resulting mixture was heated under reflux for 5 hours and then cooled to 0 C. Excess LiAlH4 was subsequently quenched with 10% NaOH aq. (6 ml) and water (6 ml). The slurry was stirred at ambient temperature for 30 minutes and Boc2O (6.15 g, 28.2 mmol) in dichloromethane (20 ml) was added. The reaction mixture was stirred over night and filtered over a short path of silica. Evaporation of the solvents and recrystallization from MTBE and pentane provided the products 3 or 4 (8.18 g).
 

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