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Chemical Structure| 1076-96-6 Chemical Structure| 1076-96-6
Chemical Structure| 1076-96-6

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Product Details of Methyl 4-vinylbenzoate

CAS No. :1076-96-6
Formula : C10H10O2
M.W : 162.19
SMILES Code : O=C(OC)C1=CC=C(C=C)C=C1
MDL No. :MFCD00017218
InChI Key :NUMHUJZXKZKUBN-UHFFFAOYSA-N
Pubchem ID :583124

Safety of Methyl 4-vinylbenzoate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Methyl 4-vinylbenzoate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1076-96-6 ]

[ 1076-96-6 ] Synthesis Path-Downstream   1~6

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YieldReaction ConditionsOperation in experiment
74% General procedure: A 15 mL Schlenk tube equipped with a stirrer bar was chargedwith CuCl (10 mol%), L7 (13 mol%), LiOMe (2.5 equiv), and theappropriate boronic ester 1 or 4 (0.375 mmol). The vessel wasthen evacuated and filled with Ar (three cycles). DMA (0.5 mL)and (Boc)2O (0.25 mmol) were added sequentially under Ar, andthe mixture was stirred at 30 for 6 h. MeI (5 equiv) was thenadded in air, and the mixture was stirred at 30 for additional2 h. The mixture was finally diluted with EtOAc and washedwith sat. aq NaCl (20 mL). The aqueous phase was furtherextracted with EtOAc (3 × 20 mL), and the combined organicphases were dried (Na2SO4) and concentrated. The residue waspurified by column chromatography [silica gel EtOAc-hexane(1:100 to 1:50)].
 

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