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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
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Chemical Structure| 139115-91-6 Chemical Structure| 139115-91-6
Chemical Structure| 139115-91-6

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Boc-NH-PEG2 (PROTAC Linker 11) is a PEG-based linker used for synthesizing PROTAC molecules.

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of Boc-NH-PEG2

CAS No. :139115-91-6
Formula : C9H19NO4
M.W : 205.25
SMILES Code : CC(C)(C)OC(=O)NCCOCCO
MDL No. :MFCD04038542
InChI Key :KSFVNEXYCULLEJ-UHFFFAOYSA-N
Pubchem ID :5220470

Safety of Boc-NH-PEG2

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H319-H301
Precautionary Statements:P264-P270-P280-P301+P310+P330-P302+P352-P305+P351+P338-P332+P313-P337+P313-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of Boc-NH-PEG2

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 139115-91-6 ]

[ 139115-91-6 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 79-08-3 ]
  • [ 139115-91-6 ]
  • [ 108466-89-3 ]
YieldReaction ConditionsOperation in experiment
2.5 g With sodium hydroxide; In tetrahydrofuran; toluene; at 45 - 50℃; To a 250mL three-necked flask were added BG05 compound 3.7g (1.0eq), toluene and THF 40ml for each, bromoacetic acid 7.6 g (3.0eq), stirred, heated to 45?50°C, then added sodium hydroxide 4.4g, and reacted overnight. After the completion of the reaction under the monitor of TLC, the reaction liquid was evaporated off, the impurities were extracted with water and ethyl acetate, and the aqueous phase was adjusted to pH=3. The aqueous phase was extracted with dichloromethane, and the dichloromethane layers were combined, dried over anhydrous sodium sulfate, and then concentrated to give 2.5g BG06 oily compound.
  • 2
  • [ 305-53-3 ]
  • [ 139115-91-6 ]
  • [ 108466-89-3 ]
  • 4
  • [ 851786-15-7 ]
  • [ 139115-91-6 ]
  • [ 1449007-11-7 ]
 

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