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Chemical Structure| 103577-40-8 Chemical Structure| 103577-40-8
Chemical Structure| 103577-40-8

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Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.

Synonyms: Lansoprazole Sulfide

4.5 *For Research Use Only !

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Product Details of Lansoprazole sulfide

CAS No. :103577-40-8
Formula : C16H14F3N3OS
M.W : 353.36
SMILES Code : FC(F)(F)COC1=C(C)C(CSC2=NC3=CC=CC=C3N2)=NC=C1
Synonyms :
Lansoprazole Sulfide
MDL No. :MFCD00834357
InChI Key :CCHLMSUZHFPSFC-UHFFFAOYSA-N
Pubchem ID :1094080

Safety of Lansoprazole sulfide

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of Lansoprazole sulfide

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 103577-40-8 ]

[ 103577-40-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 103577-40-8 ]
  • [ 21286-54-4 ]
  • [ 1245448-54-7 ]
YieldReaction ConditionsOperation in experiment
To the solution of 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl] sulfanyl]-lH-benzimidazole (100 g) present in methylenechloride (1500 ml) added potassium carbonate (58.5g) and heated the reaction mixture to reflux temperature. Added a solution of L-(-)-camphorsulfonyl chloride (106 g) in methylenechloride (500 ml) to the reaction mixture slowly at the same temperature. Stirred the reaction mixture for 6 hrs. Cooled the reaction mixture and added water to the reaction mixture. Separated the both aqueous and organic layers. Distilled off the solvent completely under reduced pressure from the organic layer. To the reaction mixture n-heptane (400 ml) was added and stirred for 45 min. Filtered the solid precipitated and washed with n-heptane. The title compound obtained as a crystalline solid. Yield: 220 grams
 

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