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Chemical Structure| 600-21-5 Chemical Structure| 600-21-5
Chemical Structure| 600-21-5

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N-DL-Me-Ala-OH is a methylated alanine derivative, commonly used in polypeptide synthesis, enhancing stability and modulating cellular metabolism.

Synonyms: H-N-Me-DL-Ala-OH; N-Methyl-DL-alanine

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Product Details of N-DL-Me-Ala-OH

CAS No. :600-21-5
Formula : C4H9NO2
M.W : 103.12
SMILES Code : CC(NC)C(O)=O
Synonyms :
H-N-Me-DL-Ala-OH; N-Methyl-DL-alanine
MDL No. :MFCD00063136
InChI Key :GDFAOVXKHJXLEI-UHFFFAOYSA-N
Pubchem ID :4377

Safety of N-DL-Me-Ala-OH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of N-DL-Me-Ala-OH

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 600-21-5 ]

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YieldReaction ConditionsOperation in experiment
61% With lithium aluminium tetrahydride; In tetrahydrofuran; at 70℃; for 16h; To a solution of 2-(methylamino)propanoic acid (10.0 g, 96.97 mmol) in THF (200 mL) wasadded LiAIH4 (5.52 g, 145.46 mmol) portionwise. The mixture was heated to 70 C for 16 h.After cooling the reaction to room temperature, water (10 mL) was added. The mixture was filtered and concentrated in vacuo. The crude residue was washed with HCI/EtOAc (2 M, 50 mL) to give the title compound (5.3 g, 61%) as a brown oil that required no fartherpurification. ?H NMR (400 MHz, CD3OD) 6 3.81 - 3.78 (m, 1H), 3.56 - 3.51 (m, IH), 3.26 -3.22 (m, IH), 2.68 (s, 3H), 1.28 (d,J= 7.2 Hz, 3H).
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