Diazirines

Diazirines are compact, photoactivatable groups commonly used in chemical biology to study protein interactions. Upon UV irradiation (typically ~350 nm), the diazirine ring forms a reactive carbene intermediate that rapidly inserts into nearby C–H, N–H, or O–H bonds, enabling covalent crosslinking of transient protein–protein or protein–ligand interactions. This makes them powerful tools for target identification and interactome mapping in live-cell environments.

Diazirines

3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine
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A4375781450754-38-796%

3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine

$441.00/1g Detail

2-[3-(But-3-yn-1-yl)-3H-diazirin-3-yl]acetic acid
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A11866542049109-24-095%

2-[3-(But-3-yn-1-yl)-3H-diazirin-3-yl]acetic acid

$168.00/25mg Detail

2-[3-(But-3-yn-1-yl)-3H-diazirin-3-yl]ethan-1-amine HCl
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A9940252089291-69-897%

2-[3-(But-3-yn-1-yl)-3H-diazirin-3-yl]ethan-1-amine HCl

$1859.00/1g Detail

2,5-Dioxopyrrolidin-1-yl 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)propanoate
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A12774222012552-32-695% (NMR)

2,5-Dioxopyrrolidin-1-yl 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)propanoate

$395.00/25mg Detail

(5-(Prop-2-yn-1-yl)-1,2-diazaspiro[2.3]hex-1-en-5-yl)methanol
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A17169532922283-70-197%

(5-(Prop-2-yn-1-yl)-1,2-diazaspiro[2.3]hex-1-en-5-yl)methanol

$337.00/25mg Detail

5-(Prop-2-yn-1-yl)-1,2-diazaspiro[2.3]hex-1-ene-5-carboxylic acid
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A17169552384877-68-197%

5-(Prop-2-yn-1-yl)-1,2-diazaspiro[2.3]hex-1-ene-5-carboxylic acid

$1347.00/100mg Detail

(3-Methyl-3H-diazirin-3-yl)methanamine hydrochloride
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A163773882516-45-297%

(3-Methyl-3H-diazirin-3-yl)methanamine hydrochloride

$972.00/250mg Detail

2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine HCl
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A85499025055-95-297%

2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine HCl

$900.00/1g Detail

3-(3-Methyl-3H-diazirine-3-yl)propionic acid
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A23698925055-86-197%

3-(3-Methyl-3H-diazirine-3-yl)propionic acid

$192.00/250mg Detail

3-(2-Bromoethyl)-3-methyl-3H-diazirine
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A103947929205-50-395%

3-(2-Bromoethyl)-3-methyl-3H-diazirine

$66.00/25mg Detail

2-(3-Methyl-3H-diazirin-3-yl)ethanol
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A12105825055-82-795%

2-(3-Methyl-3H-diazirin-3-yl)ethanol

$40.00/50mg Detail

NHS-diazirine
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A13523401239017-80-197%

NHS-diazirine

$62.00/100mg Detail

2-(3-Methyl-3H-diazirin-3-yl)ethanamine
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A77691136902-22-497%

2-(3-Methyl-3H-diazirin-3-yl)ethanamine

$241.00/100mg Detail

2-(3-Methyl-3H-diazirin-3-yl)ethyl 4-methylbenzenesulfonate
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A13377225055-84-997%

2-(3-Methyl-3H-diazirin-3-yl)ethyl 4-methylbenzenesulfonate

$406.00/100mg Detail

3-(3-Methyl-3H-diazirin-3-yl)propan-1-ol
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A39820316297-94-295%

3-(3-Methyl-3H-diazirin-3-yl)propan-1-ol

$198.00/50mg Detail

3-(3-Methyl-3H-diazirin-3-yl)propan-1-amine
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A11866451008136-15-995%

3-(3-Methyl-3H-diazirin-3-yl)propan-1-amine

$283.00/50mg Detail

tert-Butyl 1,2,5-triazaspiro[2.3]hex-1-ene-5-carboxylate
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A19459672287273-52-198%

tert-Butyl 1,2,5-triazaspiro[2.3]hex-1-ene-5-carboxylate

$235.00/100mg Detail

1,2,6-triazaspiro[2.5]oct-1-ene HCl
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A8542311803590-98-895%

1,2,6-triazaspiro[2.5]oct-1-ene HCl

$54.00/100mg Detail

1,2-Diazaspiro[2.5]oct-1-ene-6-carboxylic acid
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A112195036908-76-695%

1,2-Diazaspiro[2.5]oct-1-ene-6-carboxylic acid

$124.00/100mg Detail

tert-Butyl 1,2,6-triazaspiro[2.5]oct-1-ene-6-carboxylate
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A11866431620483-21-795%

tert-Butyl 1,2,6-triazaspiro[2.5]oct-1-ene-6-carboxylate

$23.00/100mg Detail

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