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Chemical Structure| 109583-12-2 Chemical Structure| 109583-12-2

Structure of 109583-12-2

Chemical Structure| 109583-12-2

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Product Details of [ 109583-12-2 ]

CAS No. :109583-12-2
Formula : C8H13NO2
M.W : 155.19
SMILES Code : O=C([C@H]1NC2CCC1CC2)O
MDL No. :MFCD09040768
InChI Key :YDIUZWIFYIATRZ-AHXFUIDQSA-N
Pubchem ID :10866570

Safety of [ 109583-12-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 109583-12-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 109583-12-2 ]

[ 109583-12-2 ] Synthesis Path-Downstream   1~37

  • 1
  • [ 67-56-1 ]
  • [ 109583-12-2 ]
  • H-Abo-OMe hydrochloride [ No CAS ]
  • 2
  • [ 28920-43-6 ]
  • [ 109583-12-2 ]
  • (S)-2-Aza-bicyclo[2.2.2]octane-2,3-dicarboxylic acid 2-(9H-fluoren-9-ylmethyl) ester [ No CAS ]
  • 3
  • [ 83029-36-1 ]
  • [ 109583-12-2 ]
  • [ 146144-65-2 ]
  • 4
  • [ 24424-99-5 ]
  • [ 109583-12-2 ]
  • [ 109523-16-2 ]
  • 5
  • [ 37107-48-5 ]
  • [ 109583-12-2 ]
  • (S)-2-((1R,2R)-2-Phenyl-cyclopropanecarbonyl)-2-aza-bicyclo[2.2.2]octane-3-carboxylic acid [ No CAS ]
  • 6
  • [ 109583-12-2 ]
  • [ 115238-33-0 ]
  • 7
  • 2-(1-(R)-phenethyl)-2-(S)-azabicyclo[2.2.2]oct-5-ene-3-carboxylic acid benzyl ester [ No CAS ]
  • [ 109583-12-2 ]
YieldReaction ConditionsOperation in experiment
96% With hydrogen;5%-palladium/activated carbon; In methanol; water; under 2327.23 Torr; for 2.0h; d) 2-Aza-bicyclo[2.2.2]octane-(35)-carboxylic acid[00237] To a solution of 2-((lR)-phenyl-ethyl)-2-aza-bicyclo[2.2.2]oct-5-ene-(35)-carboxylic acid benzyl ester (2.73 g, 7.86 mmol) in methanol (70 mL) was added 5% Pd-C (50% in water, 1 g). The mixture was hydrogenated under a hydrogen atmosphere (45 psi, Parr shaker) for 2 h. The mixture was filtered through Celite and concentrated in vacuo. The resulting solid was suspended in diethyl ether (50 mL), sonicated and collected by vacuum filtration. The solid was washed with diethyl ether (80 mL) and dried in vacuo at 50 0C for 16 h to afford the desired product, 2-aza-bicyclo[2.2.2]octane-(35)-carboxylic acid (1.17 g, 7.54 mmol, 96%), as an off-white solid.
  • 8
  • [ 109583-12-2 ]
  • [ 176797-39-0 ]
  • 9
  • [ 109583-12-2 ]
  • [ 1026041-14-4 ]
  • 10
  • [ 109583-12-2 ]
  • (S)-3-(2,5-Dihydro-pyrrole-1-carbonyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester [ No CAS ]
  • 11
  • [ 109583-12-2 ]
  • (S)-3-(Thiazolidine-3-carbonyl)-2-aza-bicyclo[2.2.2]octane-2-carboxylic acid tert-butyl ester [ No CAS ]
  • 12
  • [ 109583-12-2 ]
  • (3S)-2-Aza-2-tert-butyloxycarbonyl 3-[(3-azabicyclo[3.3.0]octane-3 yl) carbonyl]bicyclo[2.2.2]octane [ No CAS ]
  • 13
  • [ 109583-12-2 ]
  • 4-Phenyl-1-[(S)-3-(thiophene-2-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-butan-1-one [ No CAS ]
  • 14
  • [ 109583-12-2 ]
  • (3S)-2-aza-(6,6-dicyclopropylpentanoyl)-3-(pyrrolidin-1-ylcarbonyl)bicyclo[2.2.2]octane [ No CAS ]
  • 15
  • [ 109583-12-2 ]
  • ((1R,2R)-2-Benzyl-cyclopropyl)-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 16
  • [ 109583-12-2 ]
  • (3S)-2-aza-(6,6-dicyclopropylhexanoyl)-3-(pyrrolidin-1-ylcarbonyl)bicyclo[2.2.2]octane [ No CAS ]
  • 17
  • [ 109583-12-2 ]
  • (3S)-2-aza-2-(6,6-dicyclopropylhex-4-enoyl)-3-(pyrrolidin-1-ylcarbonyl)bicyclo[2.2.2]octane [ No CAS ]
  • 18
  • [ 109583-12-2 ]
  • (3S)-2-aza-2-(6,6-dicyclopropylhex-5-enoyl)-3-(pyrrolidin-1-ylcarbonyl)bicyclo[2.2.2]octane [ No CAS ]
  • 19
  • [ 109583-12-2 ]
  • ((1R,2R)-2-Phenyl-cyclopropyl)-[(S)-3-(thiazolidine-3-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 20
  • [ 109583-12-2 ]
  • [(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-((1R,2R)-2-thiophen-2-yl-cyclopropyl)-methanone [ No CAS ]
  • 21
  • [ 109583-12-2 ]
  • [(1R,2R)-2-(4-Fluoro-phenyl)-cyclopropyl]-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 22
  • [ 109583-12-2 ]
  • [(1R,2R)-2-(4-Methoxy-phenyl)-cyclopropyl]-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 23
  • [ 109583-12-2 ]
  • ((1R,2R)-2-Naphthalen-2-yl-cyclopropyl)-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 24
  • [ 109583-12-2 ]
  • N-Dicyclopropylmethyl-4-oxo-4-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-butyramide [ No CAS ]
  • 25
  • [ 109583-12-2 ]
  • [(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-[(1R,2R)-2-(3-trifluoromethyl-phenyl)-cyclopropyl]-methanone [ No CAS ]
  • 26
  • [ 109583-12-2 ]
  • [ 149681-03-8 ]
  • 27
  • [ 109583-12-2 ]
  • [ 149680-45-5 ]
  • 28
  • [ 109583-12-2 ]
  • 4-Phenyl-1-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-butan-1-one [ No CAS ]
  • 29
  • [ 109583-12-2 ]
  • (3-Phenyl-cyclobutyl)-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 30
  • [ 109583-12-2 ]
  • (3-Phenyl-cyclobutyl)-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 31
  • [ 109583-12-2 ]
  • ((1R,2R)-2-Phenyl-cyclopropyl)-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 32
  • [ 109583-12-2 ]
  • ((1S,2S)-2-Phenyl-cyclopropyl)-[(S)-3-(pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-methanone [ No CAS ]
  • 33
  • [ 109583-12-2 ]
  • [ 149151-23-5 ]
  • 34
  • [ 109583-12-2 ]
  • cyclo-<-Asp(OBut)-Abo-> [ No CAS ]
  • 35
  • [ 109583-12-2 ]
  • [ 149151-21-3 ]
  • 36
  • [ 109583-12-2 ]
  • S 15890 [ No CAS ]
  • 37
  • [ 109583-12-2 ]
  • cyclo<-Abo-Asp(D-Trp(Me)-Phe-N(Me)-Bzl)-> [ No CAS ]
 

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Technical Information

Categories

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[ 109583-12-2 ]

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