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[ CAS No. 1098340-27-2 ]

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2D
Chemical Structure| 1098340-27-2
Chemical Structure| 1098340-27-2
Structure of 1098340-27-2 *Storage: {[proInfo.prStorage]}

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Product Details of [ 1098340-27-2 ]

CAS No. :1098340-27-2MDL No. :MFCD11655690
Formula : C11H8F3NO2 Boiling Point : 334.5°C at 760 mmHg
Linear Structure Formula :-InChI Key :N/A
M.W :243.18Pubchem ID :45032305
Synonyms :

Computed Properties of [ 1098340-27-2 ]

TPSA : 42.1 H-Bond Acceptor Count : 5
XLogP3 : - H-Bond Donor Count : 1
SP3 : 0.18 Rotatable Bond Count : 2

Safety of [ 1098340-27-2 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1098340-27-2 ]

  • Upstream synthesis route of [ 1098340-27-2 ]
  • Downstream synthetic route of [ 1098340-27-2 ]

[ 1098340-27-2 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 1362860-87-4 ]
  • [ 1098340-27-2 ]
YieldReaction ConditionsOperation in experiment
21% for 2 h; Reflux General procedure: Methyl 3-aryl-2-azidoacrylate 1-11 (20.0 mmol) was added in one portion to a xylene refluxing solution (75 mL) which was heated for 2 h. After evaporation of the solvent, the residue was purified by column chromatography on silica gel using a petroleum ether/EtOAc mixture as eluent. Compounds 12, 18 and 19 were previously described [9b], [13] and [14].
Reference: [1] European Journal of Medicinal Chemistry, 2012, vol. 49, p. 379 - 396
  • 2
  • [ 447-61-0 ]
  • [ 1098340-27-2 ]
Reference: [1] European Journal of Medicinal Chemistry, 2012, vol. 49, p. 379 - 396
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