Structure of 168173-56-6
*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
4.5
*For Research Use Only !
Change View
Size | Price | VIP Price | US Stock |
Global Stock |
In Stock | ||
{[ item.pr_size ]} |
Inquiry
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.discount_usd) ]} {[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} |
Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]} | Inquiry {[ item.pr_usastock ]} In Stock Inquiry - | {[ item.pr_chinastock ]} {[ item.pr_remark ]} In Stock 1-2 weeks - Inquiry - | Login | - + | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
1-2weeks
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price, item.pr_usd) ]}
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
In Stock
- +
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 168173-56-6 |
Formula : | C6H5BrClN |
M.W : | 206.47 |
SMILES Code : | ClCC1=CN=C(Br)C=C1 |
MDL No. : | MFCD10697565 |
InChI Key : | OBELEIMYZJJCDO-UHFFFAOYSA-N |
Pubchem ID : | 6424658 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Num. heavy atoms | 9 |
Num. arom. heavy atoms | 6 |
Fraction Csp3 | 0.17 |
Num. rotatable bonds | 1 |
Num. H-bond acceptors | 1.0 |
Num. H-bond donors | 0.0 |
Molar Refractivity | 41.7 |
TPSA ? Topological Polar Surface Area: Calculated from |
12.89 Ų |
Log Po/w (iLOGP)? iLOGP: in-house physics-based method implemented from |
1.94 |
Log Po/w (XLOGP3)? XLOGP3: Atomistic and knowledge-based method calculated by |
2.27 |
Log Po/w (WLOGP)? WLOGP: Atomistic method implemented from |
2.43 |
Log Po/w (MLOGP)? MLOGP: Topological method implemented from |
1.91 |
Log Po/w (SILICOS-IT)? SILICOS-IT: Hybrid fragmental/topological method calculated by |
3.01 |
Consensus Log Po/w? Consensus Log Po/w: Average of all five predictions |
2.31 |
Log S (ESOL):? ESOL: Topological method implemented from |
-2.98 |
Solubility | 0.217 mg/ml ; 0.00105 mol/l |
Class? Solubility class: Log S scale |
Soluble |
Log S (Ali)? Ali: Topological method implemented from |
-2.18 |
Solubility | 1.37 mg/ml ; 0.00665 mol/l |
Class? Solubility class: Log S scale |
Soluble |
Log S (SILICOS-IT)? SILICOS-IT: Fragmental method calculated by |
-3.9 |
Solubility | 0.0258 mg/ml ; 0.000125 mol/l |
Class? Solubility class: Log S scale |
Soluble |
GI absorption? Gatrointestinal absorption: according to the white of the BOILED-Egg |
High |
BBB permeant? BBB permeation: according to the yolk of the BOILED-Egg |
Yes |
P-gp substrate? P-glycoprotein substrate: SVM model built on 1033 molecules (training set) |
No |
CYP1A2 inhibitor? Cytochrome P450 1A2 inhibitor: SVM model built on 9145 molecules (training set) |
Yes |
CYP2C19 inhibitor? Cytochrome P450 2C19 inhibitor: SVM model built on 9272 molecules (training set) |
No |
CYP2C9 inhibitor? Cytochrome P450 2C9 inhibitor: SVM model built on 5940 molecules (training set) |
No |
CYP2D6 inhibitor? Cytochrome P450 2D6 inhibitor: SVM model built on 3664 molecules (training set) |
No |
CYP3A4 inhibitor? Cytochrome P450 3A4 inhibitor: SVM model built on 7518 molecules (training set) |
No |
Log Kp (skin permeation)? Skin permeation: QSPR model implemented from |
-5.95 cm/s |
Lipinski? Lipinski (Pfizer) filter: implemented from |
0.0 |
Ghose? Ghose filter: implemented from |
None |
Veber? Veber (GSK) filter: implemented from |
0.0 |
Egan? Egan (Pharmacia) filter: implemented from |
0.0 |
Muegge? Muegge (Bayer) filter: implemented from |
1.0 |
Bioavailability Score? Abbott Bioavailability Score: Probability of F > 10% in rat |
0.55 |
PAINS? Pan Assay Interference Structures: implemented from |
0.0 alert |
Brenk? Structural Alert: implemented from |
2.0 alert: heavy_metal |
Leadlikeness? Leadlikeness: implemented from |
No; 1 violation:MW<1.0 |
Synthetic accessibility? Synthetic accessibility score: from 1 (very easy) to 10 (very difficult) |
1.86 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
1.05 g | With thionyl chloride In dichloromethane at 0 - 20℃; for 2 h; | A solution of (6-bromopyridin-3-yl)methanol (1.000 g) in DCM (10 mL) was cooled to EtOAc. Ethylene was added dropwise thionylchloride (1.260 g) in remove the ice bath after the addition. Stir for 2 hours to allow the solution to naturally warm to room temperature. Direct concentration gave 1.050 g of 2-bromo-5-(chloromethyl)pyridine. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With n-butyllithium; In tetrahydrofuran; hexane; ethyl acetate; | To a stirred solution of 8-chloro-10,11-dihydrodibenz[b,f][1,4]oxazepine (2 g) in THF (25 mL) at -78 C. was added 1.6 M hexane solution of n-butyl lithium (5.4 mL). After 25 minutes, <strong>[168173-56-6]3-chloromethyl-6-bromopyridine</strong> (1.79 g) in THF (5 mL) was added. After 30 minutes, the temperature was raised to -23 C. After 30 minutes, an excess saturated solution of NH4 Cl was added and the mixture was extracted with ether. The organic extract was dried over MgSO4 and concentrated. The residue was chromatographed over silica gel using 10% ethyl acetate in hexane as eluant. Appropriate fractions were pooled to give the title compound (2.8 g) as a thick gum. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
91% | With thionyl chloride; In dichloromethane; | This compound was synthesised as previously reported and analysis matched with literature values.[30] microscopy of the adjacent tissue immunohistochemically stained with 1E8 antibody. Scale bars indicate 100 mm. (6-Bromopyridin-3-yl)methanol (2) (2.93 g, 11.3mmol) was dissolved in dichloromethane (40mL) and treated with an excess of thionyl chloride (7mL). The reaction was monitored by TLC (33% ethyl acetate in petroleum spirits; Rf 0.81) and once complete, volatiles were removed by evaporation. The residue was then suspended in saturated NaHCO3 (50mL) and extracted with ethyl acetate (2_50mL). The organic extracts were combined, dried over MgSO4, and evaporated to dryness to yield a brown oil, which yielded a crystalline white solid upon standing. The solid was suspended in pentane and isolated by filtration, washed with pentane, and air-dried to give a crystalline colourless solid (2.13 g, 10.3mmol, 91% yield). dH (400MHz, CDCl3) 8.37 (d, 4JHH 1.9, 1H, ArH), 7.60 (dd, 3JHH 8.2, 4JHH 2.4, 1H, ArH), 7.50 (d, 3JHH 8.2, 1H, ArH), 4.54 (s, 2H, CH2). |
With sodium hydroxide; thionyl chloride; In water; toluene; acetonitrile; | To a mechanically-stirred solution of 78.12 g of thionyl chloride in 450 mL of acetonitrile at 15 C. was added a solution of 160.75 g of 3-hydroxymethyl-6-bromopyridine in 446 mL of acetonitrile over 30 minutes. The temperature rose to 22 C. during the addition, and the reaction mixture was stirred for 15 minutes at room temperature. The mixture was cooled in an ice bath, and a solution of 70 g of NaOH in 1.4 L of water was added at such a rate that the temperature did not exceed 15 C. 603 mL of toluene was added to the mixture and stirred rapidly. The layers were separated. The aqueous phase was reextracted with toluene. The combined organic phase was concentrated in vacuo to give 181.61 g of 3-chloromethyl-6-bromopyridine. | |
1.05 g | With thionyl chloride; In dichloromethane; at 0 - 20℃; for 2h; | A solution of (6-bromopyridin-3-yl)methanol (1.000 g) in DCM (10 mL) was cooled to EtOAc. Ethylene was added dropwise thionylchloride (1.260 g) in remove the ice bath after the addition. Stir for 2 hours to allow the solution to naturally warm to room temperature. Direct concentration gave 1.050 g of 2-bromo-5-(chloromethyl)pyridine. |
With thionyl chloride; In chloroform; at 0 - 20℃; for 4h; | SOCI2 (1.26 g, 10.6 mmol, 2 eq) was added drop wise to a stirred solution of compound 77 (1 g, 5.3 mmol, 1 eq) in CHCb (10 mL) at 0 C. The mixture was stirred for 4 h at room temperature. After LC-MS indicated completion, the mixture was poured into ice-water and adjusted pH = 7-8 with saturated NaHCCb, extracted with DCM (10 mL X 3). The combined organic layers was washed with brine (5 mL X 3) and dried over NaiSCU, filtered and concentrated to afford the crude product (870 mg, crude), which was used in next step directly. NMR (300 MHz, CDCb): delta 8.39 (d, J= 1.5 Hz, 1 H), 7.64 - 7.60 (m, 1 H), 7.52 (d, J= 8.1 Hz 1 H), 4.56 (s, 1 H). LCMS: (M+H)+ = 205.9, 207.9. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
4-((6-Bromopyridin-3-yl)methyl)-9-nitro-3,4,5,6-tetrahydro-2H- imidazo[2,1-b][1 ,3,6]oxadiazocine (7.2.19)A solution of <strong>[168173-56-6]2-bromo-5-(chloromethyl)pyridine</strong> (1 .0 g, 5.05 mmol) in acetone (50 ml) was treated with sodium iodide (3.8 g, 25.2 mmol). The mixture was refluxed for an hour, potassium carbonate (4.2 g, 30.3 mmol) was added to the reaction. 9-nitro-3,4,5,6-tetrahydro-2H-imidazo[2,1 - b][1 ,3,6]oxadiazocine, 7.1.3 (1 g, 5.05 mmol) was dissolved in acetone and added to the mixture and stirred overnight. The reaction mixture was filtered and evaporated. The crude was dissolved in a mixture of ethyl acetate and methanol (95%:5%) and filtered through a pad of silica. The silica was washed a few times with the ethyl acetate and methanol mixture. The washings were combined and the solvent evaporated to yield 4-((6- bromopyridin-3-yl)methyl)-9-nitro-3,4,5,6-tetrahydro-2H-imidazo[2,1 - b][1 ,3,6]oxadiazocine (1 .3 g, 3.5 mmol, 70%) with 85 % purity. The sample was further purified using prep HPLC. See Table 19 for analytical data. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
To a solution of (S)-4-methyl-2-(( 1 -((2-(trimethylsilyl)ethoxy)methyl)- 1 Htetrazol-5-yl)methyl)pentanoic acid (2950 mg, 9.0 mmol) in THF (25 ml) was added LDA (32.1ml, 22.5 mmol freshly prepared from DIPA and n-BuLi). The solution turned light yellow halfway through the base addition, and then bright yellow. The mixture was allowed to stir at -78C for 30 minutes before <strong>[168173-56-6]2-bromo-5-(chloromethyl)pyridine</strong> (2410 mg, 11.7 mmol) was added. The yellow color turned slightly red. The reaction was allowed to age for 5 hours at -78C. LC showed most of the conversion occured when the electrophile was added. The reaction went toabout 70% conversion slowly over time. The reaction was quenched with aq. NH4C1, extracted with EtOAc, separated and dried over sodium sulfate. The solution was filtered and concentrated. The residue was dissolved in water and ACN, and loaded onto a 130G C-18 column for purification. The fraction containing the desired product was collected, and evaporated under reduced pressure to afford a light yellow solid. LC-MS [M+H]: 500.2. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
for 4h;Reflux; | A solution of <strong>[168173-56-6]2-bromo-5-(chloromethyl)pyridine</strong> (3) (1.05g, 5.09mmol) in triethylphosphite (9mL) was heated to reflux for 4 h. After that time the solvent was removed by evaporation and the resultant residue dissolved in anhydrous tetrahydrofuran (30mL). To this, 4-nicotinaldehyde (4) (521 mg, 4.86mmol) was then added, followed by sodium hydride (60% w/w in mineral oil, 617 mg, 15.4mmol). The reaction was then stirred for 16 h at room temperature under an atmosphere of nitrogen gas. The reaction was then quenched by the addition of saturated NaHCO3 (25mL) and then extracted with ethyl acetate (2_25mL). The combined organic extracts were dried over MgSO4, filtered, and the filtrate evaporated to dryness under reduced pressure to yield a yellow solid that was suspended in pentane, isolated by filtration, and air-dried to yield a yellow powder (436 mg, 1.67mmol, 34% yield). m/z (ESI/O-TOF) [C12H9BrN2+H]+ 261.00249 |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
78% | General procedure: 4-Amino-5,5-disubstituted furan-2(5H)-one 1a-e (2 mmol) was dissolved in dry MeCN (25 mL) in a 50-mL round-bottom flask. The solution was cooled to 0 C by an ice-water bath, then Cs2CO3 (1.304 g, 4 mmol) was added slowly. The mixture was warmed to r.t. and stirred for 4 h. ArCH2Cl 2a-h (2.4 mmol) was added and the mixture was stirred for 12 h under reflux. The mixture was cooled to r.t. and the solid material was filtered off. The filtrate was concentrated in vacuo and the crude product was purified by flash column chromatography (silica gel, 200-300 mesh, petroleum/EtOAc 4:1 to 3:2) to give compounds 3a-x and 4a-f. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
70% | General procedure: 4-Amino-5,5-disubstituted furan-2(5H)-one 1a-e (2 mmol) was dissolved in dry MeCN (25 mL) in a 50-mL round-bottom flask. The solution was cooled to 0 C by an ice-water bath, then Cs2CO3 (1.304 g, 4 mmol) was added slowly. The mixture was warmed to r.t. and stirred for 4 h. ArCH2Cl 2a-h (2.4 mmol) was added and the mixture was stirred for 12 h under reflux. The mixture was cooled to r.t. and the solid material was filtered off. The filtrate was concentrated in vacuo and the crude product was purified by flash column chromatography (silica gel, 200-300 mesh, petroleum/EtOAc 4:1 to 3:2) to give compounds 3a-x and 4a-f. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
74% | General procedure: 4-Amino-5,5-disubstituted furan-2(5H)-one 1a-e (2 mmol) was dissolved in dry MeCN (25 mL) in a 50-mL round-bottom flask. The solution was cooled to 0 C by an ice-water bath, then Cs2CO3 (1.304 g, 4 mmol) was added slowly. The mixture was warmed to r.t. and stirred for 4 h. ArCH2Cl 2a-h (2.4 mmol) was added and the mixture was stirred for 12 h under reflux. The mixture was cooled to r.t. and the solid material was filtered off. The filtrate was concentrated in vacuo and the crude product was purified by flash column chromatography (silica gel, 200-300 mesh, petroleum/EtOAc 4:1 to 3:2) to give compounds 3a-x and 4a-f. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | General procedure: 4-Amino-5,5-disubstituted furan-2(5H)-one 1a-e (2 mmol) was dissolved in dry MeCN (25 mL) in a 50-mL round-bottom flask. The solution was cooled to 0 C by an ice-water bath, then Cs2CO3 (1.304 g, 4 mmol) was added slowly. The mixture was warmed to r.t. and stirred for 4 h. ArCH2Cl 2a-h (2.4 mmol) was added and the mixture was stirred for 12 h under reflux. The mixture was cooled to r.t. and the solid material was filtered off. The filtrate was concentrated in vacuo and the crude product was purified by flash column chromatography (silica gel, 200-300 mesh, petroleum/EtOAc 4:1 to 3:2) to give compounds 3a-x and 4a-f. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
0.73 g | With potassium carbonate; In acetonitrile; | Add N,N-dimethylacridin-4-amine (0.586g) with K2CO3 (1.160 g) to a solution of <strong>[168173-56-6]2-bromo-5-(chloromethyl)pyridine</strong> (0.853 g) in acetonitrile (10 mL). Add water (30mL), extracted with EA (50 mL×3), the combined organic layers were dried with EtOAc, 730 g of 1-((6-bromopyridin-3-yl)methyl)-N,N-dimethylpiperidin-4-amine were obtained. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
50% | To a stirred solution of compound 78 (250 mg, 2.2 mmol, 1 eq) in DMF (5 mL) at 0 C was added NaH (60% in oil, 174 mg, 4.4 mmol, 2 eq) portion wise. After the mixture was stirred at room temperature for 30 mins, a solution of compound 77 (493 mg, 2.4 mmol, 1.1 eq) in DMF (2 mL) was added drop wise at 0 C. After the addition, the reaction was allowed to warm to room temperature and stirred overnight. After LC-MS indicated completion, water (21 mL) was added drop wise at 0 C and the mixture was extracted with EA (6 mL X 3). The combined organic layers was washed with brine (5 mL X 3) and dried over Na2S04, filtered and concentrated to afford the crude product, which was purified by silica gel column to give the desired product as a yellow solid (0.31 g, 50%). *H NMR (300 MHz, CDCb): delta 8.32 (s, 1 H), 7.56 (d, J= 1.5 Hz, 1 H), 7.45 (d, J= 8.1 Hz, 1 H ), 4.50 (s, 2 H), 3.47-3.45 (m, 1 H), 2.74- 2.72 (m, 2 H), 2.32 (s, 3 H), 2.28-2.25 (m, 2 H), 1.96-1.90 (m, 2 H), 1.79-1.72 (m, 2 H). LCMS: (M+H)+ = 285.0, 287.0 |
Tags: 168173-56-6 synthesis path| 168173-56-6 SDS| 168173-56-6 COA| 168173-56-6 purity| 168173-56-6 application| 168173-56-6 NMR| 168173-56-6 COA| 168173-56-6 structure
A108429 [1126779-39-2]
2-Bromo-5-(chloromethyl)pyridine hydrochloride
Similarity: 1.00
A268869 [1033203-40-5]
2-Bromo-4-chloro-5-methylpyridine
Similarity: 0.85
A108429 [1126779-39-2]
2-Bromo-5-(chloromethyl)pyridine hydrochloride
Similarity: 1.00
A268869 [1033203-40-5]
2-Bromo-4-chloro-5-methylpyridine
Similarity: 0.85
A181429 [106651-81-4]
5-(Chloromethyl)-2-methylpyridine hydrochloride
Similarity: 0.79
A108429 [1126779-39-2]
2-Bromo-5-(chloromethyl)pyridine hydrochloride
Similarity: 1.00
A268869 [1033203-40-5]
2-Bromo-4-chloro-5-methylpyridine
Similarity: 0.85
A181429 [106651-81-4]
5-(Chloromethyl)-2-methylpyridine hydrochloride
Similarity: 0.79
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :
Total Compounds: mg
The concentration of the dissolution solution you need to prepare is mg/mL